NCT07268768 PERSONOLOGICAL STRUCTURE, COGNITIVE FUNCTIONS AND CENTRAL SENSITIZATION IN HEADACHE
| NCT ID | NCT07268768 |
| Status | Recruiting |
| Phase | — |
| Sponsor | IRCCS Centro Neurolesi Bonino Pulejo |
| Condition | Chronic and Episodic Headache |
| Study Type | OBSERVATIONAL |
| Enrollment | 64 participants |
| Start Date | 2025-11-20 |
| Primary Completion | 2028-11-20 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 64 participants in total. It began in 2025-11-20 with a primary completion date of 2028-11-20.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Headache, in its episodic and chronic forms, cannot be considered solely as an isolated neurological symptom, but as a complex condition of a bio-psycho-social nature. While in the episodic form the painful episodes occur intermittently and have a variable impact on daily life, in the chronic form the disease evolves towards persistent pain, with more significant consequences on personal, social and work functioning. The following study protocol aims to investigate in an integrated manner the neurological, cognitive and psychological mechanisms involved in headache, with particular attention to the differences between episodic and chronic forms. The main objective is to assess the neuropsychological profiles and pain response of patients, monitoring their evolution over a period of approximately six months, considering the impact of central sensitisation, personality structure and any psychopathological comorbidities on pain management and treatment adherence. The protocol adopts a multidimensional approach aimed at optimising therapeutic efficacy and improving patients' quality of life, preventing progression to chronicity.
Eligibility Criteria
Inclusion Criteria: * Age between 18 and 60 years; * Diagnosis of chronic or episodic headache; * Patients attending the Headache Outpatient Clinic. Exclusion Criteria: * Presence of severe psychiatric and neurological disorders; * Presence of oncological diseases in terminal stage
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07268768 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 60 Years, studying Chronic and Episodic Headache. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07268768 currently recruiting?
Yes, NCT07268768 is actively recruiting participants. Contact the research team at anna.anselmo@irccsme.it for enrollment information.
Where is the NCT07268768 trial being conducted?
This trial is being conducted at Messina, Italy.
Who is sponsoring the NCT07268768 clinical trial?
NCT07268768 is sponsored by IRCCS Centro Neurolesi Bonino Pulejo. The trial plans to enroll 64 participants.