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Recruiting NCT04449445

Perioperative Nutritional Optimization in Head and Neck Cancer Patients

Trial Parameters

Condition Head and Neck Cancer
Sponsor University of Illinois at Chicago
Study Type INTERVENTIONAL
Phase N/A
Enrollment 300
Sex ALL
Min Age 18 Years
Max Age N/A
Start Date 2022-05-10
Completion 2026-10
Interventions
Isocaloric and iso-nitrogenous standard enteral tube feedsNestle IMPACT AR

Brief Summary

To determine whether nutritional optimization in head and neck cancer patients undergoing major surgery will decrease post-operative wound complications. The Investigators hypothesize that nutritional supplementation with Nestle Impact Advanced Recovery (AR) will decrease the rate of wound complications after surgery

Eligibility Criteria

Inclusion Criteria: * Age \>18 years. Both men and women and members of all races and ethnic groups will be included. * Patients must be diagnosed with cancer of the head and neck and must be surgical candidates. * Patients must be indicated for major head and neck surgery, defined as surgeries with an anticipated post-surgical hospital stay of 4 or more days. Examples of major surgeries include, but are not limited to, total laryngectomy, large oral cavity, oropharyngeal, salivary gland, or soft tissue resections requiring free flap or major regional flap (e.g. pectoralis major flap), and large skull base procedures requiring extensive skull base reconstruction. * Patients must have cross-sectional body imaging (PET-CT or equivalent) performed within 4 weeks of study enrollment and available for review. * Patient must be willing to receive Nestle IMPACT Advance Recovery for five days prior to planned surgery as well as for 5 days after surgery. * Ability to understand and the willingn

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