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Recruiting NCT06253754
Pathophysiological Mechanisms and Implication of Treatment in Postural Puncture Headache
Trial Parameters
Condition Post-Dural Puncture Headache
Sponsor Umeå University
Study Type OBSERVATIONAL
Phase N/A
Enrollment 160
Sex ALL
Min Age 20 Years
Max Age 40 Years
Start Date 2024-01-30
Completion 2027-12-28
Interventions
MRI examination
Brief Summary
To improve treatment for post dural puncture headache, its pathophysiology needs to be explored. Dural puncture alters CNS dynamics; using advanced MRI, we aim to investigate PDPHs pathophysiology explained by brain movement, cerebral blood flow, CSF dynamics and the effect of epidural blood patch.
Eligibility Criteria
Inclusion Criteria: Postural puncture headache Age 20-40 Exclusion Criteria: * Other central neurological disorders except the actual * Acute medical condition * Pregnancy * Pacemaker, or other medical implants that are not MRI-compatible * Invasive procedures on the central nervous system or surgery on the spine or brain in the last 12 months.