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Recruiting NCT05478694

NCT05478694 Outcomes of Focal Ablation for Prostate Cancer

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Clinical Trial Summary
NCT ID NCT05478694
Status Recruiting
Phase
Sponsor University of Texas Southwestern Medical Center
Condition Prostate Cancer
Study Type OBSERVATIONAL
Enrollment 225 participants
Start Date 2023-02-01
Primary Completion 2026-08

Eligibility & Interventions

Sex Male only
Min Age 18 Years
Max Age 90 Years
Study Type OBSERVATIONAL

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 225 participants in total. It began in 2023-02-01 with a primary completion date of 2026-08.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

This study will be designed to define the efficacy and safety of ablative therapies in the management of localized prostate cancer and comprehensively evaluate quality of life outcomes and oncologic control following treatment.

Eligibility Criteria

Inclusion Criteria: * Men with histologically confirmed prostate adenocarcinoma diagnosed on prostate biopsy * Men with histologically confirmed local recurrence of prostate cancer diagnosed on prostate biopsy and standard of care imaging excluding locoregional or metastatic disease * Age 18-90 years. * Life expectancy \> 1 year * Ability to understand and the willingness to sign a written informed consent. Exclusion Criteria: * Anatomic abnormalities that do not allow for focal ablation * Evidence of non-organ confined disease that is not feasible for ablation * Has active urinary traction infection

Contact & Investigator

Central Contact

Sonobia Garrett

✉ Sonobia.Garrett@UTSouthwestern.edu

📞 214/645-8482

Principal Investigator

Daniel Segal, M.D.

PRINCIPAL INVESTIGATOR

University of Texas Southwestern Medical Center

Frequently Asked Questions

Who can join the NCT05478694 clinical trial?

This trial is open to male participants only, aged 18 Years or older, up to 90 Years, studying Prostate Cancer. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT05478694 currently recruiting?

Yes, NCT05478694 is actively recruiting participants. Contact the research team at Sonobia.Garrett@UTSouthwestern.edu for enrollment information.

Where is the NCT05478694 trial being conducted?

This trial is being conducted at Dallas, United States.

Who is sponsoring the NCT05478694 clinical trial?

NCT05478694 is sponsored by University of Texas Southwestern Medical Center. The principal investigator is Daniel Segal, M.D. at University of Texas Southwestern Medical Center. The trial plans to enroll 225 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: September 2026  ·  Data Methodology