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Recruiting NCT05734963

NCT05734963 ORganoid GeneratioN Study for Cancer

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Clinical Trial Summary
NCT ID NCT05734963
Status Recruiting
Phase
Sponsor Royal Marsden NHS Foundation Trust
Condition Cancer
Study Type OBSERVATIONAL
Enrollment 100 participants
Start Date 2022-04-04
Primary Completion 2031-04-12

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type OBSERVATIONAL
Interventions
DNA sequencing, RNA gene expression analysis, molecular profiling

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 100 participants in total. It began in 2022-04-04 with a primary completion date of 2031-04-12.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

ORIGINS - a multi-site sample collection study to establish patient-derived pre-clinical models for cancers

Eligibility Criteria

Inclusion Criteria: * Age 18 years or older * Patients with histologically proven or suspected cancer undergoing an interventional procedure, such as surgery or biopsy * Ability to give informed consent for biological sample collection Exclusion Criteria: * Unable to undergo sample collection * Pregnancy

Contact & Investigator

Central Contact

Ben O'Leary

✉ ben.oleary@icr.ac.uk

📞 02071535337

Principal Investigator

Ben O'Leary

PRINCIPAL INVESTIGATOR

Royal Marsden Hospital NHS Foundation Trust

Frequently Asked Questions

Who can join the NCT05734963 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Cancer. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT05734963 currently recruiting?

Yes, NCT05734963 is actively recruiting participants. Contact the research team at ben.oleary@icr.ac.uk for enrollment information.

Where is the NCT05734963 trial being conducted?

This trial is being conducted at London, United Kingdom.

Who is sponsoring the NCT05734963 clinical trial?

NCT05734963 is sponsored by Royal Marsden NHS Foundation Trust. The principal investigator is Ben O'Leary at Royal Marsden Hospital NHS Foundation Trust. The trial plans to enroll 100 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: September 2026  ·  Data Methodology