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Recruiting NCT06853405

Nutrition-based Interventions to Prevent Cognitive Decline

Trial Parameters

Condition Cognitive Dysfunction
Sponsor Instituto de Saude Publica da Universidade do Porto
Study Type INTERVENTIONAL
Phase N/A
Enrollment 120
Sex ALL
Min Age 55 Years
Max Age 85 Years
Start Date 2025-01-27
Completion 2026-05
Interventions
Nutrition-related lifestyle group sessionsCognitive trainingClinical nutrition consultations

Brief Summary

This study intends to evaluate the feasibility and the effectiveness of an innovative and integrated nutrition-based intervention addressing key modifiable risk factors for dementia while meeting participants' preferences for nutrition-related sessions. The intervention will include lifestyle group sessions regarding nutrition education and physical activity, individualized cognitive training at home, as well as clinical nutrition consultations.

Eligibility Criteria

Inclusion Criteria: * Aged from 55 to 85 years old; * At least 4 years in the regular school system; * Higher individual risk for dementia defined as a score ≥6 points on the Cardiovascular Risk Factors, Aging and Dementia Dementia Risk Score (CAIDE). Exclusion Criteria: * Montreal Cognitive Assessment (MoCA) score lower than the validated cutoff points defined as 2 standard deviations below the normative reference value for the corresponding age and education in the Portuguese population; * Having a medical condition limiting the participation in the intervention (e.g., blindness, amputation…); * Lack of autonomy in daily activities; * Diagnosis of dementia or major incapacity.

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