NCT03225677 Novel Tracer Methods to Evaluate Muscle Protein Metabolism in Cirrhosis
| NCT ID | NCT03225677 |
| Status | Recruiting |
| Phase | — |
| Sponsor | The Cleveland Clinic |
| Condition | Cirrhosis |
| Study Type | OBSERVATIONAL |
| Enrollment | 20 participants |
| Start Date | 2017-08-03 |
| Primary Completion | 2027-09-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 20 participants in total. It began in 2017-08-03 with a primary completion date of 2027-09-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
To determine the rate and mechanisms of skeletal muscle protein synthesis and breakdown in cirrhotic patients by using multiple tracers and single muscle biopsies.
Eligibility Criteria
Inclusion Criteria: * The diagnosis of cirrhosis based on liver biopsy and/or clinical, biochemical, and imaging criteria. * Patients with Child Pugh score from A5- to B7 * Control group: Subject in control group should have serum ALT and AST within normal range. Exclusion Criteria for both groups (cirrhotic and control) are: * diabetes * cancer * kidney failure * pregnancy * recent surgery (bowel resection or Gastric bypass operation) * Advanced cardiac or pulmonary disease * patient with thyroid disease \& Coagulopathy ( INR \>1.4 and platelet count \<80,000/ml)
Contact & Investigator
Srinivasan Dasarathy, MD
PRINCIPAL INVESTIGATOR
The Cleveland Clinic
Frequently Asked Questions
Who can join the NCT03225677 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Cirrhosis. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT03225677 currently recruiting?
Yes, NCT03225677 is actively recruiting participants. Contact the research team at bellara@ccf.org for enrollment information.
Where is the NCT03225677 trial being conducted?
This trial is being conducted at Cleveland, United States.
Who is sponsoring the NCT03225677 clinical trial?
NCT03225677 is sponsored by The Cleveland Clinic. The principal investigator is Srinivasan Dasarathy, MD at The Cleveland Clinic. The trial plans to enroll 20 participants.