NCT07235865 Non-Invasive Diagnosis and Monitoring of Cardiac Masses by Liquid Biopsy
| NCT ID | NCT07235865 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Niguarda Hospital |
| Condition | Cardiac Masses |
| Study Type | OBSERVATIONAL |
| Enrollment | 26 participants |
| Start Date | 2024-07-25 |
| Primary Completion | 2025-01-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 26 participants in total. It began in 2024-07-25 with a primary completion date of 2025-01-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This is a nonprofit, observational, prospective and retrospective,multicenter study in a population of young and adult patients ≥12 years with a diagnosis of a cardiac mass. The study will include both patients with masses of unknown pathological diagnosis and patients with a known histology of benign or malignant tumors. We predict a case-control allocation ratio of 1:1 between cardiac malignant tumors and benign lesions. Peripheral blood will be collected at participating centers during routine venipuncture,processed and then shipped for liquid biopsy ctDNA NGS analyses. If available, in malignant cases, matched tumor tissue samples collected as per clinical practice solid biopsies or surgery will be used for analyses. Longitudinal tracking through serial blood draws could be performed in selected cases of patients with cardiac malignancies who receive cancer treatment
Eligibility Criteria
Inclusion Criteria 1. Age ≥12 years old 2. Suspected or confirmed diagnosis of a cardiac mass of any nature as assessed by standard clinical, radiological and/or pathological procedures. Exclusion Criteria 1\. Inability of the pa ent to fully understand and sign the informed consent.
Contact & Investigator
Katia Bencardino, MD
PRINCIPAL INVESTIGATOR
Niguarda Hospital
Frequently Asked Questions
Who can join the NCT07235865 clinical trial?
This trial is open to participants of all sexes, aged 12 Years or older, studying Cardiac Masses. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07235865 currently recruiting?
Yes, NCT07235865 is actively recruiting participants. Contact the research team at katia.bencardino@ospedaleniguarda.it for enrollment information.
Where is the NCT07235865 trial being conducted?
This trial is being conducted at Milan, Italy.
Who is sponsoring the NCT07235865 clinical trial?
NCT07235865 is sponsored by Niguarda Hospital. The principal investigator is Katia Bencardino, MD at Niguarda Hospital. The trial plans to enroll 26 participants.