NCT07122739 Neurofeedback to Reduce Spontaneous Recovery of Threat Expectancy
| NCT ID | NCT07122739 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Trustees of Princeton University |
| Condition | Healthy |
| Study Type | INTERVENTIONAL |
| Enrollment | 40 participants |
| Start Date | 2025-07-17 |
| Primary Completion | 2027-12 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 40 participants in total. It began in 2025-07-17 with a primary completion date of 2027-12.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This study tests the efficacy of a new behavioral intervention with the goal of reducing spontaneous recovery of threat expectancy in healthy adults. This real-time functional magnetic resonance imaging (fMRI) neurofeedback intervention delivers feedback based on a functional connection between the prefrontal cortex and the hippocampus.
Eligibility Criteria
Inclusion Criteria: * Adults aged 18-50 * No history of psychiatric disorders or neurological disorders affecting the central nervous system. * Are not currently taking psychoactive medication or drugs of abuse. * Must be eligible to enter an MRI (i.e., no permanent metal or medical implants) * Normal color vision * Right-handed * Full reading and writing English comprehension * Must exhibit spontaneous recovery behavior as determined by an experimenter in a prescreening experimental session * Must be able to provide informed consent Exclusion Criteria: * Pregnancy (female participants) * Outside of age range * History of psychiatric or neurological disease * Currently taking psychoactive medication or drugs of abuse * Color blindness * Primary left-handedness * Less than full reading and writing English comprehension * Do not exhibit spontaneous recovery behavior as determined by an experimenter in a prescreening experimental session * Refusing to provide informed consent
Contact & Investigator
Kenneth A. Norman, Ph.D.
PRINCIPAL INVESTIGATOR
Princeton University
Frequently Asked Questions
Who can join the NCT07122739 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 50 Years, studying Healthy. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07122739 currently recruiting?
Yes, NCT07122739 is actively recruiting participants. Contact the research team at gus.hennings@princeton.edu for enrollment information.
Where is the NCT07122739 trial being conducted?
This trial is being conducted at Princeton, United States.
Who is sponsoring the NCT07122739 clinical trial?
NCT07122739 is sponsored by Trustees of Princeton University. The principal investigator is Kenneth A. Norman, Ph.D. at Princeton University. The trial plans to enroll 40 participants.