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Recruiting NCT05560724

NCT05560724 Network Properties As Biomarkers for Non-Invasive Brain Stimulation (NIBS) After Stroke

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Clinical Trial Summary
NCT ID NCT05560724
Status Recruiting
Phase
Sponsor Universitätsklinikum Hamburg-Eppendorf
Condition Stroke, Ischemic
Study Type INTERVENTIONAL
Enrollment 81 participants
Start Date 2022-07-01
Primary Completion 2025-12-31

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type INTERVENTIONAL
Interventions
Transcranial direct current stimulation (tDCS)

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 81 participants in total. It began in 2022-07-01 with a primary completion date of 2025-12-31.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The present study will evaluate the potential of cortico-cerebellar network properties derived from neuroimaging in a group of chronic stroke patients to explain inter-subject variability in responsiveness to transcranial direct current stimulation (tDCS) targeting the cortico-spinal and cortico-cerebellar network.

Eligibility Criteria

Inclusion Criteria: * patients after first-ever clinical ischemic stroke in the early (\>3 month) or later chronic (\>6 months) stage of recovery * persistent motor deficit of the upper extremity * stroke location: supratentorial * age \> 18 years * written informed consent obtained Exclusion Criteria: * contraindication against MRI \& tDCS * known epilepsy, previous epileptic seizure * electric implants such as brain stimulator * medical history suggesting more than one previous stroke * severe polyneuropathy and peripheral ischemic vascular diseases; only if they critically influence sensorimotor function of the upper limb * any active drug and alcohol abuse * any active and severe psychiatric disease (such as psychosis) * severe cognitive deficits (mini mental state examination, MMSE ≤ 23) * uncontrolled other medical problems (cardiovascular diseases, instable arrhythmia, arthritis)

Contact & Investigator

Central Contact

Robert Schulz, PD Dr. med.

✉ rschulz@uke.de

📞 0049-40-7410-0

Principal Investigator

Robert Schulz, PD Dr. med.

PRINCIPAL INVESTIGATOR

Universitätsklinikum Hamburg-Eppendorf

Frequently Asked Questions

Who can join the NCT05560724 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Stroke, Ischemic. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT05560724 currently recruiting?

Yes, NCT05560724 is actively recruiting participants. Contact the research team at rschulz@uke.de for enrollment information.

Where is the NCT05560724 trial being conducted?

This trial is being conducted at Hamburg, Germany.

Who is sponsoring the NCT05560724 clinical trial?

NCT05560724 is sponsored by Universitätsklinikum Hamburg-Eppendorf. The principal investigator is Robert Schulz, PD Dr. med. at Universitätsklinikum Hamburg-Eppendorf. The trial plans to enroll 81 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology