NCT07134881 Navigating Advanced Illness Goals And Treatment With Digital Engagement (NAVIGATE)
| NCT ID | NCT07134881 |
| Status | Recruiting |
| Phase | — |
| Sponsor | National University of Singapore |
| Condition | Paliative Care |
| Study Type | INTERVENTIONAL |
| Enrollment | 200 participants |
| Start Date | 2025-08-27 |
| Primary Completion | 2027-07-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 200 participants in total. It began in 2025-08-27 with a primary completion date of 2027-07-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this two-armed, parallel-design, pre-/post-intervention assessment clinical trial is to learn if a digital and interactive website helps to improve advance care planning (ACP) engagement among caregivers of patients with serious illness. The main questions it aims to answer are: Does the website increase ACP engagement of caregivers of patients with serious illness? Researchers will compare the digital and interactive website to the usual care (a digital booklet) to see if the digital intervention works to improve ACP engagement among caregivers. Participants who are caregivers will: * Be introduced to a digital website and asked to explore the site over the course of the study. * Complete four self-administered questionnaires (baseline, one-week, six-week, and six-month). Participants who are patients will not have any intervention assigned and will only have their observational data collected through four interviewer-administered questionnaires (baseline, one-week, six-week, and six-month)
Eligibility Criteria
1\. Patient Participants Inclusion Criteria: 1. Singapore resident aged 21years and above, 2. patient able to identify one main caregiver in the care and medical decision-making for the patient; 3. patient able to communicate in either English, Chinese, Malay or Tamil; 4. patient meeting one of the following illness criteria: 4a. Patients with brain tumours: histological and/or radiological diagnosis of glioma or brain metastases. 4b. Patients with spontaneous intracerebral haemorrhage (SICH) based on radiological diagnosis of SICH on baseline computed-tomographic scans. 4c. Patients with CKD Stage 4 and 5, identified at G4 or G5 of CKD, glomerular filtration rate (GFR) 30 ml/min or less, inclusive of kidney failure on kidney replacement therapy; and (5) Physicians assessment that ACP is appropriate for the patient by physicians.\* (\*) The attending clinicians may base the assessment of ACP appropriateness on several factors in addition to high mortality risk. As a baseline, clinicians are asked to base their assessment of high mortality risk using the validated "Surprise" question. 2\. Patient participants Exclusion Criteria: 1. Patients unable to identify a caregiver who is a medical decision-maker, 2. Patients are currently or was previously healthcare workers; or 3. Patients are diagnosed with dementia or deemed cognitively impaired as determined by the Abbreviated Mental Test. 3\. Caregiver Participants Inclusion Criteria: 1. caregivers are identified as a medical decision-maker for the patient 2. Singapore resident aged 21 years and above; and 3. able to communicate in English 4\. Caregiver Participants Exclusion Criteria: 1. caregivers are currently or were previously healthcare workers; 2. caregivers not involved in primary care of the patient (including providing care to the patient, supervision of care, or involved in making decisions regarding treatment the patient receives); or 3. caregivers diagnosed with dementia.
Contact & Investigator
Gerald Choon Huat Koh, PhD(FM)
PRINCIPAL INVESTIGATOR
Saw Swee Hock School of Public Health, National University of Singapore
Frequently Asked Questions
Who can join the NCT07134881 clinical trial?
This trial is open to participants of all sexes, aged 21 Years or older, studying Paliative Care. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07134881 currently recruiting?
Yes, NCT07134881 is actively recruiting participants. Visit ClinicalTrials.gov or contact National University of Singapore to inquire about joining.
Where is the NCT07134881 trial being conducted?
This trial is being conducted at Singapore, Singapore.
Who is sponsoring the NCT07134881 clinical trial?
NCT07134881 is sponsored by National University of Singapore. The principal investigator is Gerald Choon Huat Koh, PhD(FM) at Saw Swee Hock School of Public Health, National University of Singapore. The trial plans to enroll 200 participants.