NCT07435298 Navigated Repetitive TMS for Chronic Tinnitus
| NCT ID | NCT07435298 |
| Status | Recruiting |
| Phase | — |
| Sponsor | National University Hospital, Singapore |
| Condition | Tinnitus |
| Study Type | INTERVENTIONAL |
| Enrollment | 50 participants |
| Start Date | 2025-11-01 |
| Primary Completion | 2027-10-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 50 participants in total. It began in 2025-11-01 with a primary completion date of 2027-10-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This study is testing whether a special type of brain stimulation called neuronavigated TMS can help reduce tinnitus (ringing in the ears). 50 people with tinnitus will each receive 20 treatment sessions - 10 real treatments and 10 sham treatments in random order, with a 2-week break between them. Before starting, participants get an MRI brain scan to guide where the stimulation device is placed. Questionnaires of measuring tinnitus severity will be asked four times throughout the study to determine to check the effect of TMS on treating tinnitus.
Eligibility Criteria
Inclusion Criteria: 1. Age 21-80 years old; 2. Subjective tinnitus severity as per Tinnitus-Visual Analogue Scale of 1/10 and above (in any domain: sound, distress, Quality of Life) Exclusion Criteria: 1. Pregnancy; 2. Any metal implants inside the body that are contraindications of MRI scan; 3. Cardiac pacemakers; 4. Epilepsy with recurrent seizures; 5. Cognitively impaired patients will be excluded; 6. Claustrophobia; 7. Uncontrolled medical conditions including hypertension, diabetes mellitus and unstable angina; 8. Major depression and a history of psychotic disorders; 9. Terminal diagnosis with life expectancy \<=1 year.
Frequently Asked Questions
Who can join the NCT07435298 clinical trial?
This trial is open to participants of all sexes, aged 21 Years or older, up to 80 Years, studying Tinnitus. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07435298 currently recruiting?
Yes, NCT07435298 is actively recruiting participants. Visit ClinicalTrials.gov or contact National University Hospital, Singapore to inquire about joining.
Where is the NCT07435298 trial being conducted?
This trial is being conducted at Singapore, Singapore.
Who is sponsoring the NCT07435298 clinical trial?
NCT07435298 is sponsored by National University Hospital, Singapore. The trial plans to enroll 50 participants.