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Recruiting NCT05902351

NCT05902351 Natural History Study for Charcot Marie Tooth Disease

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Clinical Trial Summary
NCT ID NCT05902351
Status Recruiting
Phase
Sponsor Hereditary Neuropathy Foundation
Condition Charcot-Marie-Tooth Disease
Study Type OBSERVATIONAL
Enrollment 10,000 participants
Start Date 2013-11-01
Primary Completion 2029-12-31

Eligibility & Interventions

Sex All sexes
Min Age N/A
Max Age N/A
Study Type OBSERVATIONAL
All Conditions
Charcot-Marie-Tooth Disease Charcot-Marie-Tooth Charcot-Marie-Tooth Disease, Type IA Charcot-Marie-Tooth Disease Type 2A Charcot-Marie-Tooth Disease Type 2 Charcot-Marie-Tooth Disease, Type 2C Charcot-Marie-Tooth Disease Type 2A2B Charcot-Marie-Tooth Disease Type 2B2 Charcot-Marie-Tooth Disease Type 2A1 Charcot-Marie-Tooth Disease Type 4B1 Charcot-Marie-Tooth Disease, Type IB Charcot-Marie-Tooth Disease Type 2B1 Charcot-Marie-Tooth Disease Type 2U (Diagnosis) Charcot-Marie-Tooth Disease Type 4A Charcot-Marie-Tooth Disease, Type 4A, Axonal Form Charcot-Marie-Tooth Disease Type 2A2A Charcot-Marie-Tooth Disease Type 2S (Disorder) Charcot-Marie-Tooth Disease and Deafness Charcot-Marie-Tooth Disease Type 4B2 Charcot-Marie-Tooth Disease Type 4H Charcot-Marie-Tooth Disease Type 1F Charcot-Marie-Tooth Disease Type 4C Charcot-Marie-Tooth Disease Type 4E Charcot-Marie-Tooth Disease Type 1D Charcot-Marie-Tooth Disease Type 2Q (Diagnosis) Charcot-Marie-Tooth Disease Type 2A2 Charcot-Marie-Tooth Disease Type 2N (Diagnosis) Charcot-Marie-Tooth Disease Type 2B5 Charcot-Marie-Tooth Disease Type 2D Charcot-Marie-Tooth Disease Type 4D Charcot-Marie-Tooth Disease Type 2K Charcot-Marie-Tooth Disease Type 2L (Diagnosis) Charcot-Marie-Tooth Disease Type 2T Charcot-Marie-Tooth Disease Type 2I Charcot-Marie-Tooth Disease Type 2J Charcot-Marie-Tooth Disease Type 2E Charcot-Marie-Tooth Disease Type 2G Charcot-Marie-Tooth Disease Type 1C Charcot-Marie-Tooth Disease Type 2R Charcot-Marie-Tooth Disease Type 2O (Diagnosis) Charcot-Marie-Tooth Disease Type 2M Charcot-Marie-Tooth Disease Type 2P Charcot-Marie-Tooth Disease Type 2Y Charcot-Marie-Tooth Disease Type 4F (Diagnosis) Charcot-Marie-Tooth Disease Type 4B3 Charcot-Marie-Tooth Disease Type 2H HNPP X-Linked Charcot-Marie-Tooth Disease

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 10,000 participants in total. It began in 2013-11-01 with a primary completion date of 2029-12-31.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The goal of this Natural History Study for Charcot-Marie-Tooth is to acquire, record, and analyze patient-reported data and associated genetic reports, Electronic Health Records (EHRs) and clinical notes to identify the burden, diagnostic journey, and prevalence of disease that will aid scientists in their work toward finding a cure. Participants will be asked to complete a Natural History Survey.

Eligibility Criteria

Inclusion Criteria: Patients will be made aware of the study by HNF and others (referenced above) and invited to participate. Once patients have reviewed and signed electronically the informed consent document, it is attached to their file. All affected individuals with CMT/IN are eligible to participate in GRIN with proper informed consent. Children, adolescents and adults with either a confirmed diagnosis or suspected to have CMT/IN are eligible with parent and/or guardian consent. Individuals that have been clinically diagnosed through family history and/or standard clinical testing (e.g. neuro exam, EMG, NCS) and/or genetically tested or suspected to have CMT/IN (note: many mutations have not been identified yet) are eligible. Exclusion Criteria: People that do not have Charcot-Marie-Tooth or other Inherited Neuropathies

Contact & Investigator

Central Contact

Allison Moore

✉ allison@hnf-cure.org

📞 212-722-8396

Principal Investigator

Allison Moore

PRINCIPAL INVESTIGATOR

Hereditary Neuropathy Foundation

Frequently Asked Questions

Who can join the NCT05902351 clinical trial?

This trial is open to participants of all sexes, studying Charcot-Marie-Tooth Disease. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT05902351 currently recruiting?

Yes, NCT05902351 is actively recruiting participants. Contact the research team at allison@hnf-cure.org for enrollment information.

Where is the NCT05902351 trial being conducted?

This trial is being conducted at New York, United States.

Who is sponsoring the NCT05902351 clinical trial?

NCT05902351 is sponsored by Hereditary Neuropathy Foundation. The principal investigator is Allison Moore at Hereditary Neuropathy Foundation. The trial plans to enroll 10,000 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology