NCT06390878 Nationwide Research on the Rewilding of Kindergarten Yards
| NCT ID | NCT06390878 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Natural Resources Institute Finland |
| Condition | Microbial Colonization |
| Study Type | INTERVENTIONAL |
| Enrollment | 320 participants |
| Start Date | 2024-05-15 |
| Primary Completion | 2027-08-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 320 participants in total. It began in 2024-05-15 with a primary completion date of 2027-08-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Biodiversity is essential for nature and human well-being. Land use has reduced biodiversity in cities that is associated with altered commensal microbiota and a rising burden of immunological disorders among urban children. The investigators will estimate how rewilding of kindergarten yards affects commensal microbiome, prevalence of allergies, asthma, atopic dermatitis and infections, cortisol levels, cognitive skills and plasma cytokine levels of children. Our specific aims are: To assess if rewilding diversifies health-associated skin, saliva and gut microbiota and reduces infectious diseases and atopic or allergic symptoms. Assess whether the rewilding has positive effects on cognitive skills. Assess whether the rewilding changes cortisol and plasma cytokine levels. The investigators will recruit altogether 320 (160 per treatment) study subjects aged between 1-5 to questionnaire study (Task 2), from which 120 study subjects will be analyzed more detailed using microbiological and blood samples (Task 1).
Eligibility Criteria
Inclusion Criteria: * Attendance in kindergarten Exclusion Criteria: * Use of antibiotics in the year before sampling
Contact & Investigator
Aki Sinkkonen
PRINCIPAL INVESTIGATOR
Natural Resources Institute Finland
Frequently Asked Questions
Who can join the NCT06390878 clinical trial?
This trial is open to participants of all sexes, aged 1 Year or older, up to 5 Years, studying Microbial Colonization. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06390878 currently recruiting?
Yes, NCT06390878 is actively recruiting participants. Contact the research team at sanna.hurtola@luke.fi for enrollment information.
Where is the NCT06390878 trial being conducted?
This trial is being conducted at Helsinki, Finland, Tampere, Finland.
Who is sponsoring the NCT06390878 clinical trial?
NCT06390878 is sponsored by Natural Resources Institute Finland. The principal investigator is Aki Sinkkonen at Natural Resources Institute Finland. The trial plans to enroll 320 participants.