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Recruiting NCT04827498

Myocardial Ischemia Without Obstructive Coronary Stenoses

Trial Parameters

Condition Myocardial Ischemia
Sponsor Hospital San Carlos, Madrid
Study Type OBSERVATIONAL
Phase N/A
Enrollment 600
Sex ALL
Min Age 18 Years
Max Age N/A
Start Date 2017-11-08
Completion 2025-12-31
Interventions
Invasive coronary endothelium-dependent and non-endothelium-dependent physiological assessment

Brief Summary

Coronary-related myocardial ischemia can result from obstructive epicardial stenosis or non-obstructive causes including coronary microcirculatory dysfunction and vasomotor disorders. This prospective study has been created in order to provide knowledge in the field of non-obstructive coronary artery disease.

Eligibility Criteria

Inclusion Criteria: * Written informed consent available. * Age ≥ 18 years. * Patient eligible for invasive physiological assessment with adenosine and / or acetylcholine. Exclusion Criteria: * Hemodynamic instability. * Anticipated technical issues for physiology wire measurements. * Culprit vessel of acute coronary syndrome * Contraindications for adenosine administration. * Contraindications for acetylcholine test. * Reduced life expectancy (less than 1 year).

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