NCT07488325 Multimodal Assessment of Malignancy in Atypia of Undetermined Significance in Thyroid Nodules Using Ultrasound and Cytology Whole-Slide Images
| NCT ID | NCT07488325 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University |
| Condition | Thyroid Nodule |
| Study Type | OBSERVATIONAL |
| Enrollment | 396 participants |
| Start Date | 2026-03-01 |
| Primary Completion | 2026-06-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 396 participants in total. It began in 2026-03-01 with a primary completion date of 2026-06-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The prospective study aim to develop a multimodal deep learning model that integrates ultrasound images and cytological whole-slide images for more accurate malignant risk prediction of Bethesda III thyroid nodules.
Eligibility Criteria
Inclusion Criteria: * (a) Patients who underwent fine-needle aspiration of thyroid nodules and received a cytological diagnosis of Bethesda Ⅲ. * (b) Patients who subsequently underwent thyroid surgery with a definitive histopathological diagnosis of benign or malignant lesions,. * (c) Availability of at least one ultrasound image acquired prior to surgery. Exclusion Criteria: * (a) Patients without confirmation by surgical pathology,. * (b) Patients without any available or usable ultrasound images.
Contact & Investigator
Jingliang Ruan, Ph.D.
PRINCIPAL INVESTIGATOR
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Frequently Asked Questions
Who can join the NCT07488325 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 80 Years, studying Thyroid Nodule. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07488325 currently recruiting?
Yes, NCT07488325 is actively recruiting participants. Contact the research team at ruanjl3@mail.sysu.edu.cn for enrollment information.
Where is the NCT07488325 trial being conducted?
This trial is being conducted at Guangzhou, China.
Who is sponsoring the NCT07488325 clinical trial?
NCT07488325 is sponsored by Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University. The principal investigator is Jingliang Ruan, Ph.D. at Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University. The trial plans to enroll 396 participants.