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Recruiting NCT06302595

NCT06302595 MRI Guided Prostate Biopsy

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Clinical Trial Summary
NCT ID NCT06302595
Status Recruiting
Phase
Sponsor Brigham and Women's Hospital
Condition Suspected Prostate Cancer
Study Type INTERVENTIONAL
Enrollment 15 participants
Start Date 2023-08-24
Primary Completion 2026-06

Eligibility & Interventions

Sex Male only
Min Age 30 Years
Max Age N/A
Study Type INTERVENTIONAL
Interventions
MRI-guided prostate biopsy using the needle holder frame.

Eligibility Fast-Check

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What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 15 participants in total. It began in 2023-08-24 with a primary completion date of 2026-06.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

This study aims to assess the feasibility of magnetic resonance (MR) guided prostate biopsy using a needle holder frame. This frame is used to help position the needle used for the biopsy. The feasibility in this study is defined as whether the needle holder frame enables accurate tissue sampling from a suspicious region in the prostate found on an MR image. If it does, a biopsy can be carried out with the needle holder frame safely in a clinical routine. The study will be conducted during a routine MR-guided prostate biopsy procedure with an investigational needle holder frame instead of a conventional needle-guiding template.

Eligibility Criteria

Inclusion Criteria: * Either an abnormal serum prostate-specific antigen (PSA) level (\> 4ng/Ml) or a palpable nodule in the prostate on digital rectal examination or prostate MRI suspicious lesion.. * Diagnostic MRI of the prostate gland. * Age \> 30 years * Signed informed consent. * No contra-indications to MRI, i.e. no cardiac pacemaker. * No recent or ongoing active ischemic heart disease. Exclusion Criteria: * Inability to give informed consent. * Contra-indications to MRI- cardiac pacemaker, inner ear implants, non-MR compatible intracranial aneurysm clips. * Recent or ongoing active ischemic heart disease such as recent or ongoing angina.

Contact & Investigator

Central Contact

Kemal Tuncali, MD

✉ ktuncali@bwh.harvard.edu

📞 (617) 732-7631

Principal Investigator

Kemal Tuncali, MD

PRINCIPAL INVESTIGATOR

Brigham and Women's Hospital

Frequently Asked Questions

Who can join the NCT06302595 clinical trial?

This trial is open to male participants only, aged 30 Years or older, studying Suspected Prostate Cancer. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT06302595 currently recruiting?

Yes, NCT06302595 is actively recruiting participants. Contact the research team at ktuncali@bwh.harvard.edu for enrollment information.

Where is the NCT06302595 trial being conducted?

This trial is being conducted at Boston, United States.

Who is sponsoring the NCT06302595 clinical trial?

NCT06302595 is sponsored by Brigham and Women's Hospital. The principal investigator is Kemal Tuncali, MD at Brigham and Women's Hospital. The trial plans to enroll 15 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology