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Recruiting NCT06323057

NCT06323057 Modulating Reward Learning Using Transcranial Magnetic Stimulation

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Clinical Trial Summary
NCT ID NCT06323057
Status Recruiting
Phase
Sponsor Rutgers, The State University of New Jersey
Condition Behavior
Study Type INTERVENTIONAL
Enrollment 28 participants
Start Date 2024-02-14
Primary Completion 2026-04-30

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age 55 Years
Study Type INTERVENTIONAL
Interventions
Single pulse TMS to the frontal cortex

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 28 participants in total. It began in 2024-02-14 with a primary completion date of 2026-04-30.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

Our specific aim is to examine the effects of TMS on reward processing during goal-directed behavior. In these experiments the investigators will utilize a scalp-recorded brain oscillation called frontal midline theta that is believed to index the sensitivity of the cingulate cortex to reward feedback. Here the investigators will asked whether this electrophysiological signal can be modulated up or down using TMS while participants engage in decision making tasks, and if so, whether it would affect the encoding of rewards and subsequent choices during task performance.

Eligibility Criteria

Inclusion Criteria: * Be between the ages of 18 and 55 years old. * Be in stable mental and physical health. * If female, test non-pregnant. * Be willing to provide informed consent. * Be able to comply with protocol requirements and likely to complete all study procedures. Exclusion Criteria: * Contraindication to rTMS (history of neurological disorder or seizure, increased intracranial pressure, brain surgery, or head trauma with loss of consciousness for \> 15 minutes, implanted electronic device, metal in the head, or pregnancy). * History of autoimmune, endocrine, viral, or vascular disorder affecting the brain. * Life time history of mental disorders such as: Bipolar Affective disorder (BPAD), Schizophrenia, Post-traumatic Stress disorder (PTSD) or Dementia or Major Depression. * uninterruptable central nervous system medication

Frequently Asked Questions

Who can join the NCT06323057 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, up to 55 Years, studying Behavior. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT06323057 currently recruiting?

Yes, NCT06323057 is actively recruiting participants. Visit ClinicalTrials.gov or contact Rutgers, The State University of New Jersey to inquire about joining.

Where is the NCT06323057 trial being conducted?

This trial is being conducted at Newark, United States.

Who is sponsoring the NCT06323057 clinical trial?

NCT06323057 is sponsored by Rutgers, The State University of New Jersey. The trial plans to enroll 28 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology