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RecruitingNCT03932903

Mobile Health Intervention to Support Oral Chemotherapy Adherence in Adolescents and Young Adults With Leukemia

Trial Parameters

ConditionAcute Lymphoblastic Leukemia
SponsorNorthwestern University
Study TypeINTERVENTIONAL
PhaseN/A
Enrollment60
SexALL
Min Age14 Years
Max AgeN/A
Start Date2025-07-31
Completion2026-07-31
Interventions
ADAPTS (ADherence Assessments and Personalized Timely Support).

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Brief Summary

This is a small-scale micro-randomized clinical trial of a new mobile just-in-time adaptive intervention (JITAI) designed to promote oral chemotherapy adherence in adolescents and young adults (AYA) with acute lymphoblastic leukemia (ALL). The goals of this study are to determine intervention feasibility and acceptability.

Eligibility Criteria

AYA Inclusion Criteria: * Ages 14-29 * Diagnosed with acute lymphoblastic leukemia (ALL) or lymphoma * In the maintenance phase, completed at least one cycle and has at least one month of maintenance therapy remaining. * Prescribed 6-mercaptopurine (6MP) * English language proficiency * For AYA \<18, must have informed consent from their caregiver. AYA Exclusion Criteria: * Cognitive impairments that would limit ability to complete measures, determined by the medical team * Absence of inclusion criteria above. Caregiver Inclusion Criteria: * Nominated by the AYA as a primary caregiver involved in cancer care (can be a parent, relative, partner, friend) * English language proficiency Caregiver Exclusion Criteria: \- Absence of inclusion criteria above.

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