| NCT ID | NCT07438912 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Arizona |
| Condition | Suicidal Ideation |
| Study Type | INTERVENTIONAL |
| Enrollment | 90 participants |
| Start Date | 2026-03-06 |
| Primary Completion | 2029-02-28 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 90 participants in total. It began in 2026-03-06 with a primary completion date of 2029-02-28.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This study examines whether wakefulness during the biological night (2:00-4:00 AM) is associated with increased negative mood, impaired decision-making, and suicidal thoughts. Adults with a history of suicidal ideation in the past six months will complete laboratory and home-based assessments under varying levels of sleep pressure. Participants will be evaluated during late-night wakefulness and under conditions of both higher and lower sleep pressure. The goal of the study is to better understand the biological and behavioral mechanisms that may contribute to elevated suicide risk during nocturnal wakefulness.
Eligibility Criteria
Inclusion Criteria * Age 18-55 years * History of suicidal ideation within the past 6 months * Habitual bedtime between 9:00 PM and 1:00 AM * Habitual wake time between 6:00 AM and 9:00 AM * Ability to provide informed consent Exclusion Criteria: * Current suicidal intent requiring immediate clinical intervention * Diagnosis of a primary sleep disorder (e.g., untreated obstructive sleep apnea, narcolepsy) * Bipolar disorder or psychotic disorder * Substance use disorder within the past 3 months * Use of medications that significantly affect sleep or circadian rhythms * Night shift work or transmeridian travel within the past month * Medical or neurological condition that would interfere with participation * Pregnancy
Contact & Investigator
Michael A Grandner, PhD
PRINCIPAL INVESTIGATOR
University of Arizona
Frequently Asked Questions
Who can join the NCT07438912 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 55 Years, studying Suicidal Ideation. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07438912 currently recruiting?
Yes, NCT07438912 is actively recruiting participants. Contact the research team at armentamd@arizona.edu for enrollment information.
Where is the NCT07438912 trial being conducted?
This trial is being conducted at Tucson, United States.
Who is sponsoring the NCT07438912 clinical trial?
NCT07438912 is sponsored by University of Arizona. The principal investigator is Michael A Grandner, PhD at University of Arizona. The trial plans to enroll 90 participants.