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Recruiting NCT04118790

Microstructure Imaging in Stroke Patients

Trial Parameters

Condition Fatigue
Sponsor Danish Research Centre for Magnetic Resonance
Study Type OBSERVATIONAL
Phase N/A
Enrollment 90
Sex ALL
Min Age 18 Years
Max Age N/A
Start Date 2019-12-23
Completion 2023-09-01
Interventions
Clinical AssessmentMRI scan

Brief Summary

The purpose of this study is to establish a methodological framework based on existing advanced neuroimaging technologies as a new clinical neuroimaging tool for assessment of possible affected brain connections in stroke and TIA patients. Thus, providing new insights into microstructural changes that may underline why those patients experience deficits like fatigue.

Eligibility Criteria

Patient Inclusion Criteria: * Stroke or TIA (ABCD2\>4 and/or acute Diffusion-Weighted Image (DWI) lesion). * Modified Rankin Scale \<=2. * As perceived by the investigator, have the ability to comply with all requirements of the study protocol. * Have the ability to understand and sign the Informed Consents Form. * Multidimensional Fatigue Inventory score \>= 12 on general fatigue. Patient Exclusion Criteria: * The DRCMR´s general exclusion criteria for MRI research. * Pregnancy or lactation; human chorionic gonadotropin (hCG) urine test is offered for women \< 55 years. * Major medical illness (for instance: anemia, diabetes mellitus, thyroid disorders, cardiovascular disease, electrolyte imbalance, etc.) * Treated with ritalin or modafinil. * Known uncontrolled severe malignancy. * Known drug or alcohol addiction. * Tiredness due to pharmaceutical side effects, as identified by the Investigator. * Max body weight of 130 kg. * Persons who do not wish to be informed about abnormal find

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