NCT07297394 Mechanisms of Maternal Immune Tolerance in Early Pregnancy
| NCT ID | NCT07297394 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University Hospital, Basel, Switzerland |
| Condition | Pregnancy |
| Study Type | OBSERVATIONAL |
| Enrollment | 100 participants |
| Start Date | 2026-03-02 |
| Primary Completion | 2030-12 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 100 participants in total. It began in 2026-03-02 with a primary completion date of 2030-12.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This study explores the mechanisms of maternal immune tolerance in early pregnancy by characterizing immune cell profiles and functional pathways during the first trimester. The goal is to identify immunological factors that support healthy gestation and prevent complications such as miscarriages.
Eligibility Criteria
Inclusion Criteria: Blood from patients will be included before and during pregnancies (or failed implantation) conceived through IVF/ICSI (Intracytoplasmic Sperm Injection) treatment and in case of miscarriage. 1. where the patient (pregnant person) was ≥ 18 years of age. 2. where the patient (pregnant person) signed a written informed consent. Exclusion Criteria: 1. Certain maternal infections (HIV, Hepatitis B, Hepatitis C, Syphilis) 2. Patients under immunosuppressive medications (at time of blood sample collection)
Contact & Investigator
Ursula Gobrecht-Keller, MD
STUDY DIRECTOR
University Hospital of Basel
Frequently Asked Questions
Who can join the NCT07297394 clinical trial?
This trial is open to female participants only, aged 18 Years or older, studying Pregnancy. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07297394 currently recruiting?
Yes, NCT07297394 is actively recruiting participants. Contact the research team at ursula.gobrecht@usb.ch for enrollment information.
Where is the NCT07297394 trial being conducted?
This trial is being conducted at Basel, Switzerland.
Who is sponsoring the NCT07297394 clinical trial?
NCT07297394 is sponsored by University Hospital, Basel, Switzerland. The principal investigator is Ursula Gobrecht-Keller, MD at University Hospital of Basel. The trial plans to enroll 100 participants.