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Recruiting NCT07183644

NCT07183644 Maximizing Laser Therapy Success for Port-Wine Birthmarks in Pediatric Patients

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Clinical Trial Summary
NCT ID NCT07183644
Status Recruiting
Phase
Sponsor University of Texas Southwestern Medical Center
Condition Port Wine Stains
Study Type INTERVENTIONAL
Enrollment 200 participants
Start Date 2026-07
Primary Completion 2028-09

Eligibility & Interventions

Sex All sexes
Min Age 2 Months
Max Age 18 Years
Study Type INTERVENTIONAL
Interventions
Pulse Dye laserPulse Dye Laser (PDL) pulse width stackingPulse Dye Laser (PDL) followed by Nd:YAG (Neodymium-doped Yttrium Aluminum Garnet laser) laser.

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 200 participants in total. It began in 2026-07 with a primary completion date of 2028-09.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

In this study the investigators aim to optimize Port-Wine-Birthmark (PBW) laser therapy in children in order to reduce the number of laser treatments required for clearance and improve outcomes for refractory cases. This approach also seeks to reduce the frequency with which children require general anesthesia for treatment.

Eligibility Criteria

Inclusion Criteria: * Diagnosis of Port Wine Stain. * Age Range: 2mo to 18 years of age. * Stable PWS: The port wine stain should be stable, meaning there is no active inflammation or infection present, and it should not be changing in size or color due to factors like injury or disease. * signed Consent: For ethical reasons, participants must be able to provide informed consent. In the case of minors, consent would generally be required from a parent or legal guardian. General Health: Participants should generally be in good health, with no contraindications for laser therapy, such as certain skin conditions, infections, or hypersensitivity to light. Exclusion Criteria: * severe allergies to anesthesia * active skin infections or inflammation * recent laser therapy * use of Photosensitizing medications * participation in other laser studies

Contact & Investigator

Central Contact

James R Seaward, MD

✉ james.seaward@utsouthwestern.edu

📞 214 456 5250

Principal Investigator

James Seaward, MD

PRINCIPAL INVESTIGATOR

University of Texas Southwestern Medical Center

Frequently Asked Questions

Who can join the NCT07183644 clinical trial?

This trial is open to participants of all sexes, aged 2 Months or older, up to 18 Years, studying Port Wine Stains. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT07183644 currently recruiting?

Yes, NCT07183644 is actively recruiting participants. Contact the research team at james.seaward@utsouthwestern.edu for enrollment information.

Where is the NCT07183644 trial being conducted?

This trial is being conducted at Dallas, United States, Plano, United States.

Who is sponsoring the NCT07183644 clinical trial?

NCT07183644 is sponsored by University of Texas Southwestern Medical Center. The principal investigator is James Seaward, MD at University of Texas Southwestern Medical Center. The trial plans to enroll 200 participants.

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