NCT07446192 Magnetoencephalography (MEG) Pilot Study
| NCT ID | NCT07446192 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Florida |
| Condition | Essential Tremor |
| Study Type | INTERVENTIONAL |
| Enrollment | 10 participants |
| Start Date | 2026-02-17 |
| Primary Completion | 2027-08 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 10 participants in total. It began in 2026-02-17 with a primary completion date of 2027-08.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The purpose of this research is to learn more about how the brain works in people with essential tremor, and how it changes after treatment with High-Intensity Focused Ultrasound (HiFU). Essential tremor is a movement disorder that causes shaking, usually in the hands, and can make everyday tasks difficult. HiFU is a treatment that uses focused sound waves to target a small area in the brain involved in tremor. In this study, the investigators aim to understand how this treatment affects the brain's networks by using safe, non-invasive tests such as brain imaging, brain wave recordings, and movement assessments.
Eligibility Criteria
Inclusion: * Age \>50 years and \<85 years * Refractory to at least 2 first line tremor medications * Skull Density Ratio (SDR) \> = 0.35 Exclusion: * MR/MEG incompatible implants and implantable devices (ex: pacemaker) * Head tremor interfering with MEG recording * Severe depression and/or anxiety * Severe cognitive impairment
Contact & Investigator
Justin Hilliard, MD
PRINCIPAL INVESTIGATOR
University of Florida
Frequently Asked Questions
Who can join the NCT07446192 clinical trial?
This trial is open to participants of all sexes, aged 50 Years or older, up to 84 Years, studying Essential Tremor. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07446192 currently recruiting?
Yes, NCT07446192 is actively recruiting participants. Contact the research team at subeikshanan.venkatesan@neurology.ufl.edu for enrollment information.
Where is the NCT07446192 trial being conducted?
This trial is being conducted at Gainesville, United States.
Who is sponsoring the NCT07446192 clinical trial?
NCT07446192 is sponsored by University of Florida. The principal investigator is Justin Hilliard, MD at University of Florida. The trial plans to enroll 10 participants.