NCT07450612 Liquid Biopsy and Machine Learning for Early Colorectal Cancer, Adenomas, Lynch Cancers, and Residual Disease Detection
| NCT ID | NCT07450612 |
| Status | Recruiting |
| Phase | — |
| Sponsor | San Raffaele University |
| Condition | Colorectal Cancer |
| Study Type | OBSERVATIONAL |
| Enrollment | 1,200 participants |
| Start Date | 2024-01-01 |
| Primary Completion | 2031-01-15 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 1,200 participants in total. It began in 2024-01-01 with a primary completion date of 2031-01-15.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This is an multicenter study that will test the diagnostic accuracy of a blood test (i.e., a liquid biopsy) for the diagnosis of colorectal cancer (CRC), advanced adenomas (AAs), as well as Lynch-syndrome associated cancers. Additionally, a pre-planned analysis will evaluate the use of this liquid biopsy as a tool for molecular residual disease monitoring purposes.
Eligibility Criteria
Inclusion Criteria: * All individuals included in the study need to have had a colonoscopy at the time of blood sampling. * Received standard diagnostic and staging (as necessary) procedures as per local guidelines, and at least one sample was drawn before receiving any curative-intent treatment. * Received standard pathological and endoscopic diagnosis and assessment for cohort assignment Exclusion Criteria: * Lack of informed consent * Inflammatory bowel disease
Contact & Investigator
Giulia Martina Cavestro, MD, PhD
PRINCIPAL INVESTIGATOR
IRCCS San Raffaele Hospital
Frequently Asked Questions
Who can join the NCT07450612 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Colorectal Cancer. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07450612 currently recruiting?
Yes, NCT07450612 is actively recruiting participants. Contact the research team at cavestro.giuliamartina@hsr.it for enrollment information.
Where is the NCT07450612 trial being conducted?
This trial is being conducted at Milan, Italy, Milan, Italy, Milan, Italy, Milan, Italy.
Who is sponsoring the NCT07450612 clinical trial?
NCT07450612 is sponsored by San Raffaele University. The principal investigator is Giulia Martina Cavestro, MD, PhD at IRCCS San Raffaele Hospital. The trial plans to enroll 1,200 participants.
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