NCT07042087 Lifestyle for the BRAin Health - Time Restricted Eating and Mindfulness
| NCT ID | NCT07042087 |
| Status | Recruiting |
| Phase | — |
| Sponsor | St. Anne's University Hospital Brno, Czech Republic |
| Condition | Alzheimer Disease |
| Study Type | INTERVENTIONAL |
| Enrollment | 48 participants |
| Start Date | 2024-11-01 |
| Primary Completion | 2026-12 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 48 participants in total. It began in 2024-11-01 with a primary completion date of 2026-12.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The study aims to evaluate the effects of a 9-month intervention combining yoga-based mindfulness techniques, cognitive training, and nutritional counseling on cognitive function, plasma markers of neurodegeneration (tau protein), physical fitness, and metabolism in older adults at increased risk of developing Alzheimer's disease.
Eligibility Criteria
Inclusion Criteria: * Age 60-80 years * Diagnosis of Subjective Cognitive Impairment (SCI) or Mild Cognitive Impairment (MCI) * mini-mental-scale (MMSE) score between 24-30 * Positive plasma pTau217 biomarker * Stable dose of iAChE therapy (if applicable) * Ability to participate in a 9-month intervention Exclusion Criteria: * Stroke or myocardial infarction within the past year * Decompensated internal conditions (e.g., severe heart failure, kidney failure, unstable diabetes, GLP1 agonist therapy) * Long-term psychiatric treatment (except well-managed depression) * Neurological conditions affecting mobility or cognition (e.g., Parkinson's disease, severe tremor, epilepsy) * Severe sensory or motor impairment preventing protocol participation * Active cancer treated within the past 5 years * Poor anticipated compliance (e.g., transport issues, time constraints, non-cooperation) * Concurrent participation in another clinical study * Unstable iAChE medication regimen * Substance or alcohol dependence
Contact & Investigator
Kateřina Sheardova, MD. PhD.
PRINCIPAL INVESTIGATOR
The International Clinical Research Center of St. Anne's University Hospital in Brno (FNUSA-ICRC)
Frequently Asked Questions
Who can join the NCT07042087 clinical trial?
This trial is open to participants of all sexes, aged 60 Years or older, up to 80 Years, studying Alzheimer Disease. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07042087 currently recruiting?
Yes, NCT07042087 is actively recruiting participants. Visit ClinicalTrials.gov or contact St. Anne's University Hospital Brno, Czech Republic to inquire about joining.
Where is the NCT07042087 trial being conducted?
This trial is being conducted at Brno, Czechia.
Who is sponsoring the NCT07042087 clinical trial?
NCT07042087 is sponsored by St. Anne's University Hospital Brno, Czech Republic. The principal investigator is Kateřina Sheardova, MD. PhD. at The International Clinical Research Center of St. Anne's University Hospital in Brno (FNUSA-ICRC). The trial plans to enroll 48 participants.
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