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Recruiting NCT07393165

NCT07393165 Levothyroxine Treatment on Cardiac Function in Children With Subclinical Hypothyroidism

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Clinical Trial Summary
NCT ID NCT07393165
Status Recruiting
Phase
Sponsor Tanta University
Condition Levothyroxine
Study Type INTERVENTIONAL
Enrollment 40 participants
Start Date 2025-05-24
Primary Completion 2026-05-01

Eligibility & Interventions

Sex All sexes
Min Age 4 Years
Max Age 15 Years
Study Type INTERVENTIONAL
Interventions
L-thyroxine

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 40 participants in total. It began in 2025-05-24 with a primary completion date of 2026-05-01.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

This study aims to evaluate the effect of the treatment with levothyroxine on cardiac function in children with subclinical hypothyroidism.

Eligibility Criteria

Inclusion Criteria: * Age from 4 to 15 years. * Both sexes. * Patients with stable elevated thyroid-stimulating hormone (TSH) ≥ 4.5 mIU/L with normal free T4 and ft3 in different measurement 4 - 6 weeks apart. Exclusion Criteria: * Overweight and obesity * Hypertension * Previous use of levothyroxine, antiepileptic drugs, or cardiac drugs within the last 6 months. * Arrhythmia. * Congenital or acquired heart disease * Liver or kidney disease * Hyperlipidemia * Diabetes * Infectious diseases * Respiratory diseases * Malignancies

Contact & Investigator

Central Contact

Zeinab E Elshareef, MBBCH

✉ zeinabibraheem26@gmail.com

📞 00201001700194

Frequently Asked Questions

Who can join the NCT07393165 clinical trial?

This trial is open to participants of all sexes, aged 4 Years or older, up to 15 Years, studying Levothyroxine. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT07393165 currently recruiting?

Yes, NCT07393165 is actively recruiting participants. Contact the research team at zeinabibraheem26@gmail.com for enrollment information.

Where is the NCT07393165 trial being conducted?

This trial is being conducted at Tanta, Egypt.

Who is sponsoring the NCT07393165 clinical trial?

NCT07393165 is sponsored by Tanta University. The trial plans to enroll 40 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology