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Recruiting NCT06958107

NCT06958107 LCI-SAR-BSTS-CTDNA-001: Circulating Tumor DNA Liquid Biopsy in Sarcoma Patients

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Clinical Trial Summary
NCT ID NCT06958107
Status Recruiting
Phase
Sponsor Wake Forest University Health Sciences
Condition Sarcoma
Study Type OBSERVATIONAL
Enrollment 300 participants
Start Date 2025-08-21
Primary Completion 2030-01

Eligibility & Interventions

Sex All sexes
Min Age N/A
Max Age N/A
Study Type OBSERVATIONAL
Interventions
Non-Metastatic and ResectableMetastatic and Un-resectableNo evidence of disease, under surveillance

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 300 participants in total. It began in 2025-08-21 with a primary completion date of 2030-01.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The purpose of this research study is to see how well Low Pass Whole Genome Sequencing (LP-WGS) can detect circulating tumor deoxyribonucleic acid (ctDNA) in the blood of participants who have bone or soft tissue sarcoma (type of cancer).

Eligibility Criteria

Inclusion Criteria: 1. Written informed consent or assent when applicable from the participant, LAR, parent or legal guardian and HIPAA authorization for release of personal health information. 2. All ages allowed 3. Suspected or confirmed disease (must meet one of the criteria below): 1. Suspected bone or soft tissue tumor concerning for sarcoma (pending confirmation of sarcoma diagnosis) OR 2. Suspected lipomatous mass concerning for ALT or WDLS with planned surgery OR 3. Confirmed bone or soft tissue sarcoma meeting one of the criteria below: * Non-metastatic/Resectable sarcoma with either planned or currently receiving therapy * Metastatic or unresectable sarcoma, with planned or currently receiving therapy * Non-metastatic sarcoma under surveillance with no more than 1 year from completion of therapy Exclusion Criteria: * none

Contact & Investigator

Central Contact

Meg Lattanze

✉ Megan.Lattanze@advocatehealth.org

📞 980-442-4239

Principal Investigator

Johann Hsu, MD

PRINCIPAL INVESTIGATOR

Wake Forest University Health Sciences

Frequently Asked Questions

Who can join the NCT06958107 clinical trial?

This trial is open to participants of all sexes, studying Sarcoma. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT06958107 currently recruiting?

Yes, NCT06958107 is actively recruiting participants. Contact the research team at Megan.Lattanze@advocatehealth.org for enrollment information.

Where is the NCT06958107 trial being conducted?

This trial is being conducted at Charlotte, United States, Winston-Salem, United States.

Who is sponsoring the NCT06958107 clinical trial?

NCT06958107 is sponsored by Wake Forest University Health Sciences. The principal investigator is Johann Hsu, MD at Wake Forest University Health Sciences. The trial plans to enroll 300 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: July 2026  ·  Data Methodology