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Recruiting NCT06694636

Intravascular Radiofrequency Ablation of Sympathetic Nerves for the Treatment of Hepatocellular Carcinoma

Trial Parameters

Condition Hepatocellular Carcinoma
Sponsor Zhongda Hospital
Study Type INTERVENTIONAL
Phase N/A
Enrollment 5
Sex ALL
Min Age 25 Years
Max Age 75 Years
Start Date 2024-02-01
Completion 2026-02-01
Interventions
endovascular radiofrequency ablation and desympathetic nerve surgery

Brief Summary

Patients who met the inclusion criteria were treated with endovascular radiofrequency ablation and desympathetic nerve surgery. After enrollment, endovascular radiofrequency ablation and desympathetic surgery were performed. After radiofrequency ablation, the safety and efficacy of follow-up treatment will be carried out every 1 month or so, including blood routine, liver and kidney function, tumor indicators, abdominal CT/magnetic resonance, etc.

Eligibility Criteria

Inclusion Criteria: * Clinically or pathologically confirmed hepatocellular carcinoma (HCC) * Locally progressed or distant metastatic unresectable advanced HCC * Progressed after second-line therapy * Agree to participate in the study and sign the informed consent form Exclusion Criteria: * Not suitable for ablation surgery * Pregnant, lactating and planning to become pregnant * Orthostatic hypotension * Mixed liver cancer * Intestinal obstruction * Obvious bleeding tendencies and hematologic diseases * Acute or severe systemic infection; * Stroke or transient ischemic attack (TIA) within two weeks; * Acute coronary syndrome within two weeks; * Evaluated to be not suitable for this trial by investigators

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