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Recruiting NCT05553197

NCT05553197 Intersession Processes in Psychotherapeutic Treatments Using an Ecological Momentary Assessment Approach (ISA-Bell)

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Clinical Trial Summary
NCT ID NCT05553197
Status Recruiting
Phase
Sponsor Birgit Watzke
Condition Depression
Study Type INTERVENTIONAL
Enrollment 84 participants
Start Date 2022-11-01
Primary Completion 2026-05-31

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type INTERVENTIONAL
Interventions
Cognitive Behavioural Therapy (CBT)Ecological Momentary Assessment (EMA)

Eligibility Fast-Check

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What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 84 participants in total. It began in 2022-11-01 with a primary completion date of 2026-05-31.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The effects of a monitoring intervention as an add-on to face-to-face Cognitive Behavioral Therapy (CBT) for depression are assessed in this randomised trial. Monitoring consists of Ecological Momentary Assessment (EMA) of symptoms and inter-session processes via mobile phones. Twenty sessions of face-to-face CBT + EMA are compared to twenty sessions of face-to-face CBT (treatment as usual, TAU). 84 patients with mild to moderate depression will be randomised to CBT + EMA or to TAU.

Eligibility Criteria

Inclusion Criteria: * ICD-10 diagnosis of mild or moderate depression, first or recurrent episode (F32.0, F32.1, F33.0, F33.1) * PHQ-9 ≥ 5 * Possession of smartphone with internet access * Signed informed consent Exclusion Criteria: * Acute or past suicidality; self-reported * Acute addiction (F10 - F19) * Dysthymia (F34.1), postpartum depression, or severe depression (F32.3; F33.3) * PHQ-9 \> 20 * Depression not main mental health concern * Planned onset or planned change in antidepressant medication * History of psychotic symptoms, bipolar disorder, personality disorders, or organic brain disorders * Cognitive impairment or physical disability that would hinder psychotherapy or the use of a smartphone

Contact & Investigator

Central Contact

Louisa Jagmetti, M.Sc.

✉ louisa.jagmetti@psychologie.uzh.ch

📞 +41 44 635 73 28

Principal Investigator

Birgit Watzke, PhD

PRINCIPAL INVESTIGATOR

University of Zurich

Frequently Asked Questions

Who can join the NCT05553197 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Depression. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT05553197 currently recruiting?

Yes, NCT05553197 is actively recruiting participants. Contact the research team at louisa.jagmetti@psychologie.uzh.ch for enrollment information.

Where is the NCT05553197 trial being conducted?

This trial is being conducted at Zurich, Switzerland.

Who is sponsoring the NCT05553197 clinical trial?

NCT05553197 is sponsored by Birgit Watzke. The principal investigator is Birgit Watzke, PhD at University of Zurich. The trial plans to enroll 84 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology