NCT07613606 Injectable Platelet-Rich Fibrin With Minimally Invasive Non-Surgical Technique in Treatment of Periodontal Intrabony Defects
| NCT ID | NCT07613606 |
| Status | Recruiting |
| Phase | — |
| Sponsor | October 6 University |
| Condition | Platelet-Rich Fibrin |
| Study Type | INTERVENTIONAL |
| Enrollment | 40 participants |
| Start Date | 2026-03-01 |
| Primary Completion | 2026-12-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 40 participants in total. It began in 2026-03-01 with a primary completion date of 2026-12-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This study aims to clinically and radiographically evaluate the adjunctive effect of injectable platelet-rich fibrin (i-PRF) used in combination with a minimally invasive non-surgical technique for the regenerative treatment of intrabony periodontal defects.
Eligibility Criteria
Inclusion Criteria: * Patients of both genders \>18 years old, medically free of systemic diseases affecting periodontal regeneration. * Diagnosis of 'periodontitis' stage III (grades B or C). * Single-rooted and multi-rooted vital teeth in either the maxilla or the mandible. * Presence of comparable bilateral two- or three-walled intrabony defects \[probing pocket depth (PPD), \> 5 mm with intrabony defect depth ≥ 3 mm, from the alveolar crest to the defect base, at screening radiograph\] not in a furcation-involved tooth. Exclusion Criteria: * Patients with systemic illness known to affect the outcome of periodontal therapy, including diabetes, immune deficiencies, etc. * Pregnant and lactating women * Current use of any form of tobacco. * Non-surgical periodontal treatment in the past 6 months, or surgical periodontal treatment in the past 12 months. * Degree 2 or 3 mobility of the involved sites.6. * Presence of periapical pathology, acute infection, or subgingival restoration which could interfere with clinical measurements.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07613606 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Platelet-Rich Fibrin. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07613606 currently recruiting?
Yes, NCT07613606 is actively recruiting participants. Contact the research team at amirreda059@gmail.com for enrollment information.
Where is the NCT07613606 trial being conducted?
This trial is being conducted at Cairo, Egypt.
Who is sponsoring the NCT07613606 clinical trial?
NCT07613606 is sponsored by October 6 University. The trial plans to enroll 40 participants.