Influence of Air Quality on the Development and Progression of Premature Coronary Artery Disease
Trial Parameters
Brief Summary
The new global guidelines from the World Health Organization on air quality provide evidence of the damage that air pollution inflicts on human health at even lower concentrations than previously thought. Different studies have shown an increase in the incidence of coronary artery disease (CAD) in young people in recent decades. The main objective of this project is to study the impact of environmental pollutants on the premature manifestation of CAD from different epidemiological approaches and their impact on the evolution of these patients with a gender perspective. It is a retrospective analytical case-control study nested in a cohort of patients ≤40 years old with a clinical history of CAD including: ST-segment elevation myocardial infarction, non-ST-segment elevation acute coronary syndrome, unstable angina, stable angina or silent angina according to the international classification of diseases.
Eligibility Criteria
CASES: Inclusion Criteria: * Women and men between 18 and 40 years old with a diagnosis of coronary artery disease coded in their medical records in Galicia Exclusion Criteria: * Not having a postal code and primary care center assigned in their medical records in Galicia CONTROL Inclusion Criteria: * Women and men between 18 and 40 years old with no diagnosis or history of CAD or other coronary disease coded in their medical records Exclusion Criteria: * Present with non-ischemic coronary diseas. * Have a serious condition that affects or decreases life expectancy. * Do not have a postal code or primary care center assigned in their medical records in Galicia