← Back to Clinical Trials
Recruiting NCT05127252

NCT05127252 Impact of the Microbiome on Time to Pregnancy and Pregnancy Outcomes in Fertile Women Attempting to Conceive

◆ AI Clinical Summary
Plain-language summary for patients
Clinical Trial Summary
NCT ID NCT05127252
Status Recruiting
Phase
Sponsor Karolinska Institutet
Condition Pregnancy Complications
Study Type OBSERVATIONAL
Enrollment 500 participants
Start Date 2023-04-10
Primary Completion 2026-03-10

Eligibility & Interventions

Sex Female only
Min Age 18 Years
Max Age 40 Years
Study Type OBSERVATIONAL
Interventions
Vaginal and rectal microbiome and metabolome

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 500 participants in total. It began in 2023-04-10 with a primary completion date of 2026-03-10.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

This study aims to investigate the microbiome of women with previously proven fertility who plan to become pregnant.

Eligibility Criteria

Inclusion Criteria: * Women with a previous live birth in the past 5 years and planning a new pregnancy with the same male partner. * 18-40 years of age * Swedish personal identity number and a Swedish address (to send a sampling self-kit) * Sufficient understanding of spoken and written Swedish or English to provide informed consent and complete the web-based questionnaire. Exclusion Criteria: * Women who do not have a child yet and plan to cease their contraception.

Contact & Investigator

Central Contact

Lars Holmgren, Professor

✉ lars.holmgren@ki.se

📞 046734036794

Principal Investigator

Lars Holmgren, Professor

STUDY CHAIR

Karolinska Institutet

Frequently Asked Questions

Who can join the NCT05127252 clinical trial?

This trial is open to female participants only, aged 18 Years or older, up to 40 Years, studying Pregnancy Complications. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT05127252 currently recruiting?

Yes, NCT05127252 is actively recruiting participants. Contact the research team at lars.holmgren@ki.se for enrollment information.

Where is the NCT05127252 trial being conducted?

This trial is being conducted at Stockholm, Sweden, Uppsala, Sweden.

Who is sponsoring the NCT05127252 clinical trial?

NCT05127252 is sponsored by Karolinska Institutet. The principal investigator is Lars Holmgren, Professor at Karolinska Institutet. The trial plans to enroll 500 participants.

Related Trials

ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology