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Recruiting NCT04696159

NCT04696159 Impact of Per Oral Pyloromyotomy (POP) on Glycemic Control in Diabetes

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Clinical Trial Summary
NCT ID NCT04696159
Status Recruiting
Phase
Sponsor Matthew Allemang
Condition Diabetes Mellitus
Study Type INTERVENTIONAL
Enrollment 40 participants
Start Date 2023-01-04
Primary Completion 2026-06

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type INTERVENTIONAL
Interventions
Pyloromyotomy

Eligibility Fast-Check

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What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 40 participants in total. It began in 2023-01-04 with a primary completion date of 2026-06.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

This study will assess changes in glycemic control in 40 patients with diabetes who undergo per-oral pyloromyotomy (POP) for medically refractory gastroparesis.

Eligibility Criteria

Inclusion Criteria: 1. Patients 18 years of age and older 2. Patients with gastroparesis with an average HbA1c\> 7.5% over the past 3 months 3. Patient that have a diagnosis of gastroparesis established by documented delayed gastric emptying by either a wireless motility capsule study or a nuclear gastric emptying study, with no evidence of gastric obstruction. 4. Patients are able to complete all study requirements Exclusion Criteria: 1. Patients \<18 years of age 2. Patients with gastroparesis with an average HbA1c\< 7.5% over the past 3 months 3. Patients unable or refuse to complete the study requirements 4. Patients who are unable or refuse to wear a CGM sensor 5. Patients with insulin pumps 6. Patients who already use a CGM

Contact & Investigator

Central Contact

Deanne Nash, RN

✉ nashd@ccf.org

📞 216-445-0953

Principal Investigator

Mathew Allemang, MD

PRINCIPAL INVESTIGATOR

The Cleveland Clinic

Frequently Asked Questions

Who can join the NCT04696159 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Diabetes Mellitus. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT04696159 currently recruiting?

Yes, NCT04696159 is actively recruiting participants. Contact the research team at nashd@ccf.org for enrollment information.

Where is the NCT04696159 trial being conducted?

This trial is being conducted at Cleveland, United States.

Who is sponsoring the NCT04696159 clinical trial?

NCT04696159 is sponsored by Matthew Allemang. The principal investigator is Mathew Allemang, MD at The Cleveland Clinic. The trial plans to enroll 40 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology