NCT05906810 Impact of Non-surgical Periodontal Therapy in the Improvement of Early Endothelial Dysfunction in Subjects With Peri-implantitis and Peri-implant Mucositis
| NCT ID | NCT05906810 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Catania |
| Condition | Atherosclerosis |
| Study Type | INTERVENTIONAL |
| Enrollment | 90 participants |
| Start Date | 2020-10-05 |
| Primary Completion | 2025-11-20 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 90 participants in total. It began in 2020-10-05 with a primary completion date of 2025-11-20.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
A double-blind randomized-controlled clinical trial is conducted in order to evaluate the impact of non-surgical periodontal treatment on endothelial dysfunction parameters in subjects with peri-implantitis/peri-implant mucositis and without any cardiovascular disease.
Eligibility Criteria
PERI-IMPLANTITIS GROUP Inclusion Criteria: • Clinically diagnosed with peri-implantitis according to the EFP/AAP 2017 criteria. Exclusion Criteria: * Periodontal treatment, implant surgery, antibiotics, NSAIDs, immunosuppressants during the last 6 months. * Pregnancy. * Cardiovascular Diseases. PERI-IMPLANT MUCOSITIS GROUP Inclusion Criteria: • Clinically diagnosed with peri-implant mucositis according to the EFP/AAP 2017 criteria. Exclusion Criteria: * Periodontal treatment, implant surgery, antibiotics, NSAIDs, immunosuppressants during the last 6 months. * Pregnancy. * Cardiovascular Diseases. HEALTHY GROUP Inclusion Criteria: • Clinically diagnosed with healthy periodontum withouth periodontitis history according to the EFP/AAP 2017 criteria. Exclusion Criteria: * Scaling, antibiotics, NSAIDs, immunosuppressants during the last 6 months. * Pregnancy. * Cardiovascular Diseases.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT05906810 clinical trial?
This trial is open to participants of all sexes, studying Atherosclerosis. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT05906810 currently recruiting?
Yes, NCT05906810 is actively recruiting participants. Contact the research team at gaetano.isola@unict.it for enrollment information.
Where is the NCT05906810 trial being conducted?
This trial is being conducted at Catania, Italy.
Who is sponsoring the NCT05906810 clinical trial?
NCT05906810 is sponsored by University of Catania. The trial plans to enroll 90 participants.