NCT07152912 Impact of Isoflurane and Sevoflurane on Oxidative Stress in Patients Undergoing Laparoscopic Cholecystectomy
| NCT ID | NCT07152912 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Ain Shams University |
| Condition | Isoflurane |
| Study Type | INTERVENTIONAL |
| Enrollment | 80 participants |
| Start Date | 2025-09-04 |
| Primary Completion | 2026-03-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 80 participants in total. It began in 2025-09-04 with a primary completion date of 2026-03-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The primary aim of this work is to assess the impact of exposure to isoflurane or sevoflurane as an inhalation anesthetic on the oxidative stress and inflammatory conditions in patients undergoing elective moderate invasive surgery (laparoscopic cholecystectomy).
Eligibility Criteria
Inclusion Criteria: * Age from 20 to 60 years. * Both sexes. * American Society of Anesthesiologists (ASA) Physical Status I-II. * Undergoing elective laparoscopic cholecystectomy under general anesthesia. Exclusion Criteria: * Refusal of participation in the study by patients. * Diabetes (type I or II), endocrine system, and immune system diseases. * Chronic infection and sepsis. * Cardiac condition as classified bythe New York Heart Association (NYHA) \> class II. * Hepatic disease: INR \> 1.5, and/or albumin \< 2.5 g/dL. * Renal disease: glomerular filtration rate (GFR) \< 85 ml/min. * Mental and neurological disorders.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07152912 clinical trial?
This trial is open to participants of all sexes, aged 20 Years or older, up to 60 Years, studying Isoflurane. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07152912 currently recruiting?
Yes, NCT07152912 is actively recruiting participants. Contact the research team at eman.adel@med.asu.edu.eg for enrollment information.
Where is the NCT07152912 trial being conducted?
This trial is being conducted at Cairo, Egypt.
Who is sponsoring the NCT07152912 clinical trial?
NCT07152912 is sponsored by Ain Shams University. The trial plans to enroll 80 participants.