NCT02948972 Impact of Complete Surgery of Colorectal Deep Infiltrating Endometriosis on Fertility
| NCT ID | NCT02948972 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University Hospital, Lille |
| Condition | Endometriosis |
| Study Type | INTERVENTIONAL |
| Enrollment | 120 participants |
| Start Date | 2016-11-17 |
| Primary Completion | 2026-05 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 120 participants in total. It began in 2016-11-17 with a primary completion date of 2026-05.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The ENDOFERT Study is an open, multicenter, randomized, parallel-group, controlled trial. This study includes patients presenting colorectal DIE and infertility. Patients will be randomized in two parallel-groups; one group underwent complete surgery of colorectal DIE prior to ART and the other group underwent ART alone (ratio 1:1)
Eligibility Criteria
Inclusion Criteria: * Primary and secondary infertility * Indication for IVF * Persistent pain related to endometriosis with analgesic medical treatment failure * Persistent pain including at least one of the following digestive symptoms related to endometriosis: Dyschesia / Sub-occlusive syndrome / Rectal bleeding / Painful defecation * Colorectal deep infiltrating endometriosis : Whatever lesion size / With at least rectal serosal involvement / Confirmed by MRI and 1 different investigation: vaginal ultrasound echography or coloscopic CT scan or rectal endoscope ultrasound * Eligible for DIE surgery Exclusion Criteria: * Contraindication to pregnancy or to IVF * Viral risk * Previous IVF cycle(s) * Previous colorectal surgery * Need of myomectomy during surgery * The use of oocytes donor
Contact & Investigator
Pierre Collinet, MD, PhD
PRINCIPAL INVESTIGATOR
University Hospital, Lille
Frequently Asked Questions
Who can join the NCT02948972 clinical trial?
This trial is open to female participants only, aged 18 Years or older, up to 38 Years, studying Endometriosis. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT02948972 currently recruiting?
Yes, NCT02948972 is actively recruiting participants. Contact the research team at pierre.collinet@chru-lille.fr for enrollment information.
Where is the NCT02948972 trial being conducted?
This trial is being conducted at Clermont-Ferrand, France, Lille, France, Paris, France, Poissy, France and 1 additional location.
Who is sponsoring the NCT02948972 clinical trial?
NCT02948972 is sponsored by University Hospital, Lille. The principal investigator is Pierre Collinet, MD, PhD at University Hospital, Lille. The trial plans to enroll 120 participants.