Trial Parameters
Eligibility Fast-Check
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Brief Summary
The experimental study investigates which metabolic responses of calcium and parathyroid hormone are observable in blood and urine in a cohort of 41 healthy adults following a sequence of different exposures: low-calcium water first and high-calcium water afterward.
Eligibility Criteria
Inclusion Criteria: * Body mass index ≥ 18 and \< 30 * Maintenance of diet and physical activity lifestyle throughout the duration of the study * Acceptance of informed consent Exclusion Criteria: * Consumption of water with calcium \> 150 mg/L * Pregnancy (as established by self-declaration), breastfeeding, menopause * Inability to follow the study protocol * Cardiac, vascular, renal, and oncological disease * Neuropsychiatric disease, developmental disorders * Disease or past surgery affecting the gastrointestinal tract * Drugs that interfere with bone (e.g. corticosteroids) or with fluid balance (e.g. diuretics)