NCT07138872 Hemodynamic Effects of Surgical Position in Prone vs. Supine Percutaneous Nephrolithotomy
| NCT ID | NCT07138872 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Gaziosmanpasa Research and Education Hospital |
| Condition | Percutaneous Nephrolithotomy (PCNL) |
| Study Type | INTERVENTIONAL |
| Enrollment | 84 participants |
| Start Date | 2025-06-01 |
| Primary Completion | 2025-12-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 84 participants in total. It began in 2025-06-01 with a primary completion date of 2025-12-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This prospective, randomized controlled study evaluates the hemodynamic effects of prone and supine positions during percutaneous nephrolithotomy (PNL) for large kidney stones. Surgical position may influence intraoperative and postoperative hemodynamic stability. Prone positioning can increase intrathoracic pressure and reduce venous return, whereas supine positioning may provide greater hemodynamic stability. A total of 84 patients will be randomized to undergo PNL in prone or supine positions. Primary outcomes include changes in hemodynamic parameters during surgery. Results may guide surgical position selection, especially in patients with potential hemodynamic risk.
Eligibility Criteria
Inclusion Criteria: * ASA physical status I-III * Presence of renal calculi indicated for PNL Exclusion Criteria: * Pregnancy * Uncontrolled coagulopathy * Previous renal surgery * Severe cardiac, pulmonary, or neurological disease * Preoperative urinary tract infection (non-sterile urine culture) * Surgery duration \<60 minutes or \>120 minutes * Preoperative blood transfusion * Multiple access tracts
Contact & Investigator
Burak Arslan, CLINICAL PROFESSOR OF UROLOGY
STUDY DIRECTOR
Gaziosmanpaşa Training and Research Hospital, Urology Department, Istanbul, Türkiye
Frequently Asked Questions
Who can join the NCT07138872 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 80 Years, studying Percutaneous Nephrolithotomy (PCNL). Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07138872 currently recruiting?
Yes, NCT07138872 is actively recruiting participants. Contact the research team at arifkecebas@gmail.com for enrollment information.
Where is the NCT07138872 trial being conducted?
This trial is being conducted at Istanbul, Turkey (Türkiye).
Who is sponsoring the NCT07138872 clinical trial?
NCT07138872 is sponsored by Gaziosmanpasa Research and Education Hospital. The principal investigator is Burak Arslan, CLINICAL PROFESSOR OF UROLOGY at Gaziosmanpaşa Training and Research Hospital, Urology Department, Istanbul, Türkiye. The trial plans to enroll 84 participants.