| NCT ID | NCT04620343 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Haukeland University Hospital |
| Condition | Exercise Induced Laryngeal Obstruction (EILO) |
| Study Type | INTERVENTIONAL |
| Enrollment | 350 participants |
| Start Date | 2021-01-01 |
| Primary Completion | 2023-12-31 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 350 participants in total. It began in 2021-01-01 with a primary completion date of 2023-12-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Exercise induced laryngeal obstruction (EILO) is a common cause of exertional breathing problems in young individuals, caused by paradoxical inspiratory adduction of laryngeal structures, and diagnosed by continuous visualization of the larynx during high intensity exercise.
Eligibility Criteria
Inclusion Criteria: * EILO with CLE score at peak exercise graded as ≥ 2 at glottic or supraglottic level and * Respiratory complaints to an extent that the patient wants further treatment and follow-up. Exclusion Criteria: * Breathing problems caused by disorders other than EILO or well controlled asthma. * Perceived to be unable to perform repeated maximal cardiopulmonary treadmill exercise tests, or failing to accept the procedures required for repeated successful CLE tests, or unable to perform any of the other examinations required by the protocol. * Abnormal anatomy at rest in the laryngeal region or the upper airways. * Age below 12 years
Contact & Investigator
Hege H Clemm, MD, PhD
PRINCIPAL INVESTIGATOR
Haukeland University Hospital
Frequently Asked Questions
Who can join the NCT04620343 clinical trial?
This trial is open to participants of all sexes, aged 12 Years or older, studying Exercise Induced Laryngeal Obstruction (EILO). Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT04620343 currently recruiting?
Yes, NCT04620343 is actively recruiting participants. Contact the research team at hege.synnove.havstad.clemm@helse-bergen.no for enrollment information.
Where is the NCT04620343 trial being conducted?
This trial is being conducted at Bergen, Norway.
Who is sponsoring the NCT04620343 clinical trial?
NCT04620343 is sponsored by Haukeland University Hospital. The principal investigator is Hege H Clemm, MD, PhD at Haukeland University Hospital. The trial plans to enroll 350 participants.