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Recruiting NCT06533228

NCT06533228 Helmsley 3.0: Abbreviated MRE

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Clinical Trial Summary
NCT ID NCT06533228
Status Recruiting
Phase
Sponsor Children's Hospital Medical Center, Cincinnati
Condition Crohn's Disease
Study Type OBSERVATIONAL
Enrollment 300 participants
Start Date 2024-09-01
Primary Completion 2027-02-28

Eligibility & Interventions

Sex All sexes
Min Age 10 Years
Max Age N/A
Study Type OBSERVATIONAL
Interventions
Magnetic Resonance Imaging (MRI) or Magnetic Resonance Enterography (MRE)

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 300 participants in total. It began in 2024-09-01 with a primary completion date of 2027-02-28.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The purpose of our study is to compare an abbreviated magnetic resonance imaging (MRI) of the bowel or magnetic resonance enterography (MRE) protocol to a conventional, standard of care MRE in children and adults with Crohn's Disease.

Eligibility Criteria

Inclusion Criteria: * Established Crohn's disease diagnosis in patients 10 and older * Undergoing clinical magnetic resonance enterography (MRE) examinations for any reason(s) below * Staging/ restaging/ follow- up of intestinal inflammation * Evaluation of known or suspected luminal narrowing/ stricturing disease * Evaluation of known or suspected internal penetrating disease Exclusion Criteria: * Undergoing initial imaging for suspected Crohn's disease where the diagnosis of Crohn's disease has yet to be definitively established * New Crohn's disease diagnosis, undergoing baseline imaging * Isolated colonic disease * Known or suspected pregnancy * Contraindication to magnetic resonance imaging (MRI) * Ileostomy or prior ileal resection * Less than 10 years of age * Unable or unwilling to follow imaging procedures * Non- English speaking

Contact & Investigator

Central Contact

Tanita Dean

✉ Tanita.Dean@cchmc.org

📞 (513) 803-0853

Principal Investigator

Jonathan Dillman

PRINCIPAL INVESTIGATOR

CCHMC

Frequently Asked Questions

Who can join the NCT06533228 clinical trial?

This trial is open to participants of all sexes, aged 10 Years or older, studying Crohn's Disease. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT06533228 currently recruiting?

Yes, NCT06533228 is actively recruiting participants. Contact the research team at Tanita.Dean@cchmc.org for enrollment information.

Where is the NCT06533228 trial being conducted?

This trial is being conducted at Rochester, United States, New York, United States.

Who is sponsoring the NCT06533228 clinical trial?

NCT06533228 is sponsored by Children's Hospital Medical Center, Cincinnati. The principal investigator is Jonathan Dillman at CCHMC. The trial plans to enroll 300 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology