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Recruiting NCT06928116

NCT06928116 Heat thErapy And mobiLity in COVID-19 Survivors

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Clinical Trial Summary
NCT ID NCT06928116
Status Recruiting
Phase
Sponsor University of Nebraska
Condition Long COVID
Study Type INTERVENTIONAL
Enrollment 99 participants
Start Date 2025-01-16
Primary Completion 2028-08-31

Eligibility & Interventions

Sex All sexes
Min Age 50 Years
Max Age 90 Years
Study Type INTERVENTIONAL
Interventions
Heat therapySham ControlWalking

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 99 participants in total. It began in 2025-01-16 with a primary completion date of 2028-08-31.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

Post-acute sequelae of SARS-CoV-2 infection (PASC) is becoming a major risk factor for chronic diseases, with older adults and those with underlying health conditions at risk of developing persistent mobility limitations and disabilities. Although exercise intervention is a common strategy to restore functional capacity, it may not be feasible or enticing to many people with PASC. This clinical trial seeks to establish the tolerability and efficacy of at home lower-body heat therapy for improving functional capacity along with metabolic and vascular health in late-middle aged and older adults with PASC, also known as "long COVID".

Eligibility Criteria

Inclusion Criteria: * Between the ages of 50 and 90 years * Free from orthopedic limitations that would prohibit performing leg exercise * BMI \< 40 kg/m2 and weigh \< 400lbs * Previously contracted Covid-19 and have persistent symptoms such as a fatigue or decline in physical function, for at least 2 months following SARS-CoV-2 infection Exclusion Criteria: * Unable to give written informed consent * Women who are pregnant, breastfeeding, or likely to become pregnant within the next 6 months * Women who are taking hormone therapy * Claustrophobia * Orthopedic limitations that would prohibit them from walking * Currently enrolled in an exercise-based or respiratory muscle rehabilitation program.

Contact & Investigator

Central Contact

Gwenael Layec, PhD

✉ unovrl@unomaha.edu

📞 402-554-3779

Principal Investigator

Gwenael Layec, PhD

PRINCIPAL INVESTIGATOR

University of Nebraska

Frequently Asked Questions

Who can join the NCT06928116 clinical trial?

This trial is open to participants of all sexes, aged 50 Years or older, up to 90 Years, studying Long COVID. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT06928116 currently recruiting?

Yes, NCT06928116 is actively recruiting participants. Contact the research team at unovrl@unomaha.edu for enrollment information.

Where is the NCT06928116 trial being conducted?

This trial is being conducted at Omaha, United States.

Who is sponsoring the NCT06928116 clinical trial?

NCT06928116 is sponsored by University of Nebraska. The principal investigator is Gwenael Layec, PhD at University of Nebraska. The trial plans to enroll 99 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: July 2026  ·  Data Methodology