NCT07625462 Hearing and Brain Development Cohort in Children and Adolescents
| NCT ID | NCT07625462 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University |
| Condition | Hearing Loss |
| Study Type | OBSERVATIONAL |
| Enrollment | 5,000 participants |
| Start Date | 2026-05-20 |
| Primary Completion | 2030-12-31 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 5,000 participants in total. It began in 2026-05-20 with a primary completion date of 2030-12-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This bidirectional observational cohort study aims to establish a Hearing and Brain Development (HBD) cohort in children and adolescents with hearing loss across different hearing management pathways, including hearing aid fitting, cochlear implantation, auditory brainstem implantation, gene therapy, and follow-up without intervention, as well as in a normal-hearing control group. Participants will undergo longitudinal assessments of hearing, speech, language, neurodevelopment, and multimodal brain function.
Eligibility Criteria
Inclusion Criteria: * Age no more than 18 years. * For the HA/CI/ABI/GT/FU groups: behavioral or pure-tone hearing threshold \>=20 dB HL, or air-conduction ABR \>=35 dB nHL; For the normal-hearing control group: participants diagnosed as normal hearing by experienced physicians. Exclusion Criteria: * Inability to cooperate with study testing procedures.
Contact & Investigator
Hao Wu
PRINCIPAL INVESTIGATOR
Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine
Frequently Asked Questions
Who can join the NCT07625462 clinical trial?
This trial is open to participants of all sexes, up to 18 Years, studying Hearing Loss. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07625462 currently recruiting?
Yes, NCT07625462 is actively recruiting participants. Contact the research team at liyuncmm@126.com for enrollment information.
Where is the NCT07625462 trial being conducted?
This trial is being conducted at Shanghai, China.
Who is sponsoring the NCT07625462 clinical trial?
NCT07625462 is sponsored by Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University. The principal investigator is Hao Wu at Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine. The trial plans to enroll 5,000 participants.