NCT07595705 Gingival Hyperpigmentation Treatment
| NCT ID | NCT07595705 |
| Status | Recruiting |
| Phase | Phase 2 |
| Sponsor | Cairo University |
| Condition | Gingival Pigmentation |
| Study Type | INTERVENTIONAL |
| Enrollment | 30 participants |
| Start Date | 2025-08-01 |
| Primary Completion | 2027-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
In Phase 2, researchers evaluate early signs of effectiveness. You may be randomized to receive the active treatment or a comparator. Monitoring continues closely.
This trial targets 30 participants in total. It began in 2025-08-01 with a primary completion date of 2027-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
It is a clinical study conducted to evaluate the effect of vitamin C and Glucathonine injection of pigmented gingival tissue versus surgical removal by scalpel
Eligibility Criteria
Inclusion Criteria: The selection criteria were done according to Gingival pigmentation index is as follows (Dummett and Bolden)10: 1. Score0:absence of pigmentation 2. Score1:spotsofbrowntoblackcolororpigments 3. Score2:browntoblackpatchesbutnotdiffusepigmentation 4. Score3:diffuse brown to black pigmentation,marginal,and attached. Patients who have Dummett and Bolden index score 1, 2, or 3 will be included in addition to the following criteria: 1. above 18yrs 2. systemically free 3. physiologic gingival hyperpigmentation related to esthetic region 4. well maintained oral hygiene and willing to undergo minor surgical procedures Exclusion Criteria: 1. systemic diseases associated with pathological hyperpigmentation or improper delayed wound healing (uncontrolled diabetes, autoimmune diseases, etc.) 2. pregnant and lactating mothers 3. usage of chlorhexidine or povidone iodine 4. Local causes (smoking) 5. periodontal diseases (plaque and non-plaque induced gingivitis or periodontitis) 6. non compliant patients
Contact & Investigator
Nourhan A Abdullah, Phd
PRINCIPAL INVESTIGATOR
Lecturer at faculty of dentistry, Fayoum university
Frequently Asked Questions
Who can join the NCT07595705 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Gingival Pigmentation. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
What phase is the NCT07595705 trial and what does that mean for participants?
Phase 2 trials evaluate whether the treatment shows signs of effectiveness while continuing to monitor safety. More participants are enrolled than in Phase 1 to help refine the treatment protocol.
Is NCT07595705 currently recruiting?
Yes, NCT07595705 is actively recruiting participants. Contact the research team at naa14@fayoum.edu.eg for enrollment information.
Where is the NCT07595705 trial being conducted?
This trial is being conducted at Al Fayyum, Egypt.
Who is sponsoring the NCT07595705 clinical trial?
NCT07595705 is sponsored by Cairo University. The principal investigator is Nourhan A Abdullah, Phd at Lecturer at faculty of dentistry, Fayoum university. The trial plans to enroll 30 participants.