| NCT ID | NCT06506786 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Oregon |
| Condition | Gut Microbiome |
| Study Type | INTERVENTIONAL |
| Enrollment | 20 participants |
| Start Date | 2023-07-01 |
| Primary Completion | 2024-12-31 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 20 participants in total. It began in 2023-07-01 with a primary completion date of 2024-12-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The purpose of this research is to explore what types of microbes are present on garden-fresh versus store-bought fruits and vegetables, as well as how they might affect the human gut microbiome.
Eligibility Criteria
Inclusion Criteria: \- Exclusion Criteria: * Body mass index (BMI) greater than or equal to 35 or less than or equal to 18. * Age under 18 or over 45. * Female who is pregnant or lactating. * Irregular bowel movements and/or stool consistency. * Plans to travel, move residences, or other major life change during the study period (August-October 2023). * Unable to speak, read, and write English. * Use of any of the following drugs within the last 6 months: * systemic antibiotics, antifungals, antivirals or antiparasitics (intravenous, intramuscular, or oral); * oral, intravenous, intramuscular, nasal or inhaled corticosteroids; * cytokines; * methotrexate or immunosuppressive cytotoxic agents; * large doses of commercial probiotics consumed (greater than or equal to 108 cfu or organisms per day) - includes tablets, capsules, lozenges, chewing gum or powders in which probiotic is a primary component. Ordinary dietary components such as fermented beverages/milks, yogurts, foods do not apply. * Acute disease at the time of enrollment (defer sampling until subject recovers). Acute disease is defined as the presence of a moderate or severe illness with or without fever. * History of cancer except for squamous or basal cell carcinomas of the skin that have been medically managed by local excision. * Unstable dietary history as defined by major changes in diet during the previous month, where the subject has eliminated or significantly increased a major food group in the diet. * Recent history of chronic alcohol consumption defined as more than five 1.5-ounce servings of 80 proof distilled spirits, five 12-ounce servings of beer or five 5-ounce servings of wine per day. * Any confirmed or suspected condition/state of immunosuppression or immunodeficiency (primary or acquired) including HIV infection. * Major surgery of the GI tract, with the exception of cholecystectomy and appendectomy, in the past five years. Any major bowel resection at any time. * History of active uncontrolled gastrointestinal disorders or diseases including: * inflammatory bowel disease (IBD) including ulcerative colitis (mild-moderate-severe), Crohn's disease (mild-moderate-severe), or indeterminate colitis; * irritable bowel syndrome (IBS) (moderate-severe); * persistent, infectious gastroenteritis, colitis or gastritis, persistent or chronic diarrhea of unknown etiology, Clostridium difficile infection (recurrent) or Helicobacter pylori infection (untreated); * chronic constipation.
Contact & Investigator
Gwynne Mhuireach, PhD
PRINCIPAL INVESTIGATOR
University of Oregon
Frequently Asked Questions
Who can join the NCT06506786 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 45 Years, studying Gut Microbiome. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06506786 currently recruiting?
Yes, NCT06506786 is actively recruiting participants. Contact the research team at gwynhwyf@uoregon.edu for enrollment information.
Where is the NCT06506786 trial being conducted?
This trial is being conducted at Eugene, United States.
Who is sponsoring the NCT06506786 clinical trial?
NCT06506786 is sponsored by University of Oregon. The principal investigator is Gwynne Mhuireach, PhD at University of Oregon. The trial plans to enroll 20 participants.