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Recruiting Phase 4 NCT06226129

NCT06226129 Gadopiclenol in Contrast Enhanced MRI of the Prostate

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Clinical Trial Summary
NCT ID NCT06226129
Status Recruiting
Phase Phase 4
Sponsor Columbia University
Condition Prostate Cancer
Study Type INTERVENTIONAL
Enrollment 150 participants
Start Date 2024-02-14
Primary Completion 2027-02-01

Eligibility & Interventions

Sex Male only
Min Age 18 Years
Max Age N/A
Study Type INTERVENTIONAL
Interventions
Gadopiclenol

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

Phase 4 studies follow an already-approved treatment in real-world conditions to monitor long-term safety and effectiveness.

This trial targets 150 participants in total. It began in 2024-02-14 with a primary completion date of 2027-02-01.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The fundamental aim of this study is to show that the novel contrast agent Gadopiclenol (Elucirem), with its high relaxivity, facilitates increased contrast enhancement and improved differentiation of clinically significant prostate cancer on Prostate MRI, as categorized by the PI-RADS v2 classification categories.

Eligibility Criteria

Inclusion Criteria: * Scheduled to undergo a clinically indicated MRI of the prostate with contrast. * Scheduled to undergo, or likely to be scheduled to undergo, a prostate MRI-US fusion biopsy with histology results available within 6 months of their MRI. Exclusion Criteria: * Prisoner * Have already begun therapeutic treatment for prostate cancer including surgery (TURP, prostatectomy), radiotherapy, hormone therapy or chemotherapy. * Patients with end stage renal failure who are on dialysis. Patients who have chronic kidney disease or acute kidney injury are contraindicated for MRI per FDA and ACR (American College of Radiologists) guidelines and would thus be excluded as well.

Contact & Investigator

Central Contact

Nicolas Bloch, MD

✉ bnb2134@cumc.columbia.edu

📞 212 305 0519

Principal Investigator

Nicolas Bloch, MD

PRINCIPAL INVESTIGATOR

Columbia University

Frequently Asked Questions

Who can join the NCT06226129 clinical trial?

This trial is open to male participants only, aged 18 Years or older, studying Prostate Cancer. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

What phase is the NCT06226129 trial and what does that mean for participants?

Phase 4 studies are conducted after a treatment has been approved. They monitor long-term safety and real-world effectiveness in a broader patient population.

Is NCT06226129 currently recruiting?

Yes, NCT06226129 is actively recruiting participants. Contact the research team at bnb2134@cumc.columbia.edu for enrollment information.

Where is the NCT06226129 trial being conducted?

This trial is being conducted at New York, United States.

Who is sponsoring the NCT06226129 clinical trial?

NCT06226129 is sponsored by Columbia University. The principal investigator is Nicolas Bloch, MD at Columbia University. The trial plans to enroll 150 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology