NCT06703736 Functional and Morphological Characterization of Multiple Osteochondromas Disorder
| NCT ID | NCT06703736 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Istituto Ortopedico Rizzoli |
| Condition | Hereditary Multiple Osteochondromas |
| Study Type | OBSERVATIONAL |
| Enrollment | 60 participants |
| Start Date | 2025-05-21 |
| Primary Completion | 2026-09-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 60 participants in total. It began in 2025-05-21 with a primary completion date of 2026-09-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The main purpose of the study is the characterization of functional and morphological alterations due to multiple osteochondromas in a pediatric and adult population through the identification of relevant anthropometric and functional parameters. The morphological and functional data, supplemented with clinical and postural data, will allow the characterization of the disease with an holistic approach that can provide important information to properly assess timing for surgical treatments and to improve the quality of life of these patients. Another goal of the study is the assessment and the validation of novel instruments and tools to measure joint mobility and bone deformity. These instruments should be easy-to-use and designed to be operated locally by the patients themselves and/or in small clinics by operators with little training and no specific high-technical knowledge. The final goal of the study is the assessment of the quality of life and balance perception of patients, using questionnaires.
Eligibility Criteria
Inclusion Criteria: For multiple osteochondromas cohort inclusion criteria are: * clinical and/or molecular diagnosis of Multiple Osteochondromas; * male and female subjects; * age minors: 6-17 years at enrollment and adult age: 18-40 years at enrollment; * collection of appropriate informed consent; * ability to walk a linear path without aids; * presence of multiple osteochondromas localized at lower limbs; * ability to undergo all procedures required by the protocol. For healthy cohort inclusion criteria are: * absence of neuro-muskuloskeletal or other limb-limiting conditions in the lower limbs; * male and female subjects; * age minors: 6-17 years at enrollment and adult age: 18-40 years at enrollment; * collection of appropriate informed consent; * ability to undergo all procedures required by the protocol. Exclusion Criteria: * Persons who do not fit the inclusion criteria; * Any reason which, in the opinion of the investigator, would result in the inability of the participant to comply with the protocol. * BMI equal to or greater than 30.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT06703736 clinical trial?
This trial is open to participants of all sexes, aged 6 Years or older, up to 40 Years, studying Hereditary Multiple Osteochondromas. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06703736 currently recruiting?
Yes, NCT06703736 is actively recruiting participants. Contact the research team at paolo.caravaggi@ior.it for enrollment information.
Where is the NCT06703736 trial being conducted?
This trial is being conducted at Bologna, Italy.
Who is sponsoring the NCT06703736 clinical trial?
NCT06703736 is sponsored by Istituto Ortopedico Rizzoli. The trial plans to enroll 60 participants.