NCT07099963 Frequency and Severity of Respiratory Acidosis During One-lung Ventilation, a Retrospective Pilot Study to Compare Clinician Settings and Those Proposed by the VentilO Application

Eligibility & Interventions

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What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 100 participants in total. It began in 2025-08-01 with a primary completion date of 2025-12.

Brief Summary

One-lung ventilation is a mechanical ventilation method frequently used during several thoracic surgeries. One-lung ventilation requires the use of protective ventilation to limit ventilator-induced injury and reduce postoperative respiratory complications. Protective ventilation during one-lung ventilation is specific since tidal volumes are applied by definition to one lung, and it is recommended to use lower tidal volumes, down to 4 ml/kg of ideal body weight. This approach requires individualized ventilation parameters, which differs from the conventional or two-lung ventilation, and there are no clear recommendations regarding respiratory rate adjustment to ensure adequate gas exchange.

Eligibility Criteria

Inclusion Criteria: * Adults (≥ 18 years old) * Patients intubated and undergoing one-lung ventilation during thoracic surgery * Volume-controlled ventilation mode used intraoperatively Exclusion Criteria: * Arterial blood gas data unavailable during one-lung ventilation * Missing demographic data (sex, height, actual weight)

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