Trial Parameters
Brief Summary
This study aims to investigate the neural mechanisms involved in the development of reach-to-grasp function in infants. Reaching and grasping are crucial motor skills that develop early in infancy and are essential for later motor and cognitive milestones. Understanding how these skills emerge and the underlying neural processes can provide valuable insights into both typical and atypical development. The study will focus on infants aged 3 to 9 months, a critical period for the development of reach-to-grasp skills. A total of 100 infants will be recruited, including 50 full-term infants and 50 preterm infants (born \<36 weeks gestational age). Reach-to-grasp function will be evaluated through a cross-sectional assessment at a single time point. Functional near-infrared spectroscopy (fNIRS) will be used as the brain imaging technique to measure brain activity during the reach-to-grasp task. The use of fNIRS will allow for a non-invasive assessment of neural activity in real time, providing insights into the brain mechanisms supporting the development of motor skills. The findings may offer important information about the neural basis of motor development in infancy, particularly in the context of preterm birth.
Eligibility Criteria
Inclusion Criteria: * 3-9 months old * can tolerate the fNIRS cap * performs at least 2 grapsing attempts with one hand within one minute when prompting the hand with a toy Exclusion Criteria: * history of periferal neurological lesion such as plexus brachialis lesion * presence of epilepsia, congenital brain malformation, * no informed consent * severe visual impairments * syndromal or genetical diseases resulting into developmental delay