NCT07573995 Feasibility and Effects of Inspiratory Muscle Training Combined With Blood Flow Restriction for Frail Older Adults
| NCT ID | NCT07573995 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Taipei Medical University |
| Condition | Frailty Syndrome |
| Study Type | INTERVENTIONAL |
| Enrollment | 30 participants |
| Start Date | 2026-08-19 |
| Primary Completion | 2027-07-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 30 participants in total. It began in 2026-08-19 with a primary completion date of 2027-07-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This randomized controlled trial study aims to evaluate the feasibility and preliminary efficacy of a combined inspiratory muscle training (IMT) and blood flow restriction (BFR) intervention in frail older adults. Outcomes of interest include feasibility, physical function, respiratory muscle strength, handgrip strength, five-times sit-to-stand performance, body composition, frailty level, fall efficacy, blood pressure, and adverse events.
Eligibility Criteria
Inclusion Criteria: * Community-dwelling adults aged 65 years and older who are classified as at least "vulnerable" using the Clinical Frailty Scale (score ≥4). * Participants must have no cognitive impairment and be able to follow commands, as assessed by the Mini-Mental State Examination (MMSE). Exclusion Criteria: * (1) are unable to participate in exercise (e.g., due to severe musculoskeletal disorders) * (2) have high-risk factors for exercise, such as uncontrolled hypertension (\>150 mmHg systolic blood pressure (SBP) / \>90 mmHg diastolic blood pressure (DBP), coagulation disorders, and deep venous thrombosis * (3) have hematological disorders or are using hematology related-medications * (4) have significant comorbidities, including a history of stroke, diabetes with severe complications, or cardiovascular diseases * (5) chronic lung conditions (e.g., obstructive pulmonary disease, asthma), and * (6) have participated in a structured exercise training program within the past 3 months at a frequency exceeding three sessions per week.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07573995 clinical trial?
This trial is open to participants of all sexes, aged 65 Years or older, studying Frailty Syndrome. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07573995 currently recruiting?
Yes, NCT07573995 is actively recruiting participants. Contact the research team at ptsai@tmu.edu.tw for enrollment information.
Where is the NCT07573995 trial being conducted?
This trial is being conducted at Taipei, Taiwan.
Who is sponsoring the NCT07573995 clinical trial?
NCT07573995 is sponsored by Taipei Medical University. The trial plans to enroll 30 participants.